Serum 17β-estradiol inversely correlates with circulating group 2 innate lymphoid cells in a cohort of asthmatic patients

Serum 17β-estradiol inversely correlates with circulating group 2 innate lymphoid cells in a cohort of asthmatic patients

IntroductionAsthma is a chronic airway inflammatory disorder that demonstrates a strong clinical bias in females of reproductive age. In this study we evaluated group 2 innate lymphoid cells (ILC2) that play a now well-defined role in allergy and asthma. ILC2 are rare immune cells that demonstrate a...

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Bibliographic Details
Main Authors: Elizabeth J. Myers, Samuel E. Aamodt, Thomas P. Huecksteadt, Robert Paine, Mustafa Mir-Kasimov, Christopher A. Reilly, Sean J. Callahan, Karl A. Sanders, Kristi J. Warren
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
asthma
estrogen
progesterone
neutrophils
eosinophils
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1555228/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1555228/full

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