Study of the electrophysiological mechanisms of anticonvulsant action of the original levetiracetam analog the compound GIZH-290
The study used the method of cobalt epilepsy, which allows rats with long-term implanted electrodes in the cortical and subcortical structures of the brain to monitor the dynamics of the formation and migration of Epi-foci for a long time. It was found that in the control at the 1st stage of develop...
Saved in:
Main Authors: | T. A. Voronina, S. A. Litvinova, N. A. Gladysheva, А. A. Yakovleva |
---|---|
Format: | Article |
Language: | Russian |
Published: |
LLC “Publisher OKI”
2021-09-01
|
Series: | Фармакокинетика и Фармакодинамика |
Subjects: | |
Online Access: | https://www.pharmacokinetica.ru/jour/article/view/270 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Effect of the compound GIZH -290 and levetiracetam on epileptic activity in rat brain structures on EEG models of bemegrid-induced seizures
by: T. A. Voronina, et al.
Published: (2021-06-01) -
Determination of a novel anticonvulsant drug GIZh-290 in rat plasma by liquid chromatography–tandem mass spectrometry
by: P. O. Bochkov, et al.
Published: (2022-01-01) -
ELECTROPHYSIOLOGICAL AND NEUROCHEMICAL STUDIES OF THE MECHANISMS OF THE ANTICONVULSANT EFFECT OF THE NEW ORIGINAL COMPOUND GIZH-298
by: S. A. Litvinova, et al.
Published: (2016-12-01) -
4-BENZOYLPYRIDINE OXIME DERIVATIVE (GIZH-298) VERSUS VALPROIC ACID: THE ANTICONVULSANT POTENTIAL EFFECT IN A MODEL OF EPILEPSY IN RATS WITH COBALT-INDUCED LESIONS
by: I. O. Gaydukov, et al.
Published: (2017-08-01) -
Quantification of a potential anticonvulsant drug GIZh-298 in rat plasma by liquid chromatography-mass spectrometry
by: P. O. Bochkov, et al.
Published: (2022-12-01)