Clinical and neurophysiological features of mental disorders in patients with HIV infection
Summary. Te aim of the study was to study the clinical signifcance of changes in bioelectric activity for the purpose of identifying them as biological markers of mental disorders in patients with HIV infection. A cross-sectional study was conducted to diagnose mental disorders and search for neurop...
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| Format: | Article |
| Language: | Russian |
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Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation
2019-02-01
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| Series: | Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева |
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| Online Access: | https://www.bekhterevreview.com/jour/article/view/216 |
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| author | N. G. Neznanov N. B. Khalezova M. A. Hobeysh N. G. Zakharova M. Ya. Kissin |
| author_facet | N. G. Neznanov N. B. Khalezova M. A. Hobeysh N. G. Zakharova M. Ya. Kissin |
| author_sort | N. G. Neznanov |
| collection | DOAJ |
| description | Summary. Te aim of the study was to study the clinical signifcance of changes in bioelectric activity for the purpose of identifying them as biological markers of mental disorders in patients with HIV infection. A cross-sectional study was conducted to diagnose mental disorders and search for neurophysiological markers in 62 patients with HIV infection at the St. Petersburg Center for the Prevention and Control of HIV and Infectious Diseases.Results: 50% of patients with HIV infection without abuse disorders have mental disorders characterized mainly by adaptive reactions and mild cognitive impairment. Normal indicators of bioelectrical activity were determined in 16.1% of 62 patients. In the majority of patients (59.7%), bioelectrical activity was determined with a predominance of excitation in the medio-different areas and a decrease in activity of the cerebral cortex. In 41.9% of patients, the processes of CNS excitation were increased in the form of an intensifcation of the reaction to photostimulation. Neurophysiological differences were revealed in patients with neurotic and stress-related disorders and organic changes in the CNS. For neurotic disorders in comparison with organic disorders, the EEG was normal or the disorganized type with predominance of alpha and beta activity were more likely, while in the case of organic disorders the desynchronous type of EEG was more ofen noted. Te development of psycho-organic syndrome in HIV patients is confrmed by deep restructuring of bioelectrical activity in the anterior parts of the brain. |
| format | Article |
| id | doaj-art-c81d0ce199cf4b0dbd886cdbede28de4 |
| institution | Matheson Library |
| issn | 2313-7053 2713-055X |
| language | Russian |
| publishDate | 2019-02-01 |
| publisher | Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation |
| record_format | Article |
| series | Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева |
| spelling | doaj-art-c81d0ce199cf4b0dbd886cdbede28de42025-08-03T13:06:36ZrusFederal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian FederationОбозрение психиатрии и медицинской психологии имени В.М. Бехтерева2313-70532713-055X2019-02-0104536310.31363/2313-7053-2018-4-53-6215Clinical and neurophysiological features of mental disorders in patients with HIV infectionN. G. Neznanov0N. B. Khalezova1M. A. Hobeysh2N. G. Zakharova3M. Ya. Kissin4St. Petersburg State Medical University named afer I.P. PavlovSt. Petersburg State Medical University named afer I.P. Pavlov; Center for the Prevention and Control of AIDS and Infectious DiseasesSt. Petersburg State Medical University named afer I.P. PavlovCenter for the Prevention and Control of AIDS and Infectious DiseasesSt. Petersburg State Medical University named afer I.P. PavlovSummary. Te aim of the study was to study the clinical signifcance of changes in bioelectric activity for the purpose of identifying them as biological markers of mental disorders in patients with HIV infection. A cross-sectional study was conducted to diagnose mental disorders and search for neurophysiological markers in 62 patients with HIV infection at the St. Petersburg Center for the Prevention and Control of HIV and Infectious Diseases.Results: 50% of patients with HIV infection without abuse disorders have mental disorders characterized mainly by adaptive reactions and mild cognitive impairment. Normal indicators of bioelectrical activity were determined in 16.1% of 62 patients. In the majority of patients (59.7%), bioelectrical activity was determined with a predominance of excitation in the medio-different areas and a decrease in activity of the cerebral cortex. In 41.9% of patients, the processes of CNS excitation were increased in the form of an intensifcation of the reaction to photostimulation. Neurophysiological differences were revealed in patients with neurotic and stress-related disorders and organic changes in the CNS. For neurotic disorders in comparison with organic disorders, the EEG was normal or the disorganized type with predominance of alpha and beta activity were more likely, while in the case of organic disorders the desynchronous type of EEG was more ofen noted. Te development of psycho-organic syndrome in HIV patients is confrmed by deep restructuring of bioelectrical activity in the anterior parts of the brain.https://www.bekhterevreview.com/jour/article/view/216hiv infectionneurophysiological markers of mental disordersneurotic and stress-related disordersorganic disorders |
| spellingShingle | N. G. Neznanov N. B. Khalezova M. A. Hobeysh N. G. Zakharova M. Ya. Kissin Clinical and neurophysiological features of mental disorders in patients with HIV infection Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева hiv infection neurophysiological markers of mental disorders neurotic and stress-related disorders organic disorders |
| title | Clinical and neurophysiological features of mental disorders in patients with HIV infection |
| title_full | Clinical and neurophysiological features of mental disorders in patients with HIV infection |
| title_fullStr | Clinical and neurophysiological features of mental disorders in patients with HIV infection |
| title_full_unstemmed | Clinical and neurophysiological features of mental disorders in patients with HIV infection |
| title_short | Clinical and neurophysiological features of mental disorders in patients with HIV infection |
| title_sort | clinical and neurophysiological features of mental disorders in patients with hiv infection |
| topic | hiv infection neurophysiological markers of mental disorders neurotic and stress-related disorders organic disorders |
| url | https://www.bekhterevreview.com/jour/article/view/216 |
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