Purposeful search and characteristic of anti-inflammatory activity of sodium (3-R-2-оxo-2Н-[1,2,4]triazino[2,3-c]quinazolin-6-yl)alkylcarboxylates and their halogen containing analogues

QR Code

Purposeful search and characteristic of anti-inflammatory activity of sodium (3-R-2-оxo-2Н-[1,2,4]triazino[2,3-c]quinazolin-6-yl)alkylcarboxylates and their halogen containing analogues

Aim. The approaches for creating novel agents with anti-inflammatory activity among sodium (3-R-2-oxo-2Н-[1,2,4]triazino[2,3-c]quinazolin-6-yl)alkylcarboxylates and their halogen containing analogues were described in presented article. Methods and results. Mentioned methods have been based on c...

Full description

Saved in:

Bibliographic Details
Main Authors:	V. V. Yakubovska, N. М. Seredinska, О. Yu. Voskoboynik, G. І. Stepanyuk, S. І. Kovalenko
Format:	Article
Language:	English
Published:	Zaporizhzhia State Medical and Pharmaceutical University 2016-04-01
Series:	Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
Subjects:	sodium (3-R-2-oxo-2Н-[1 2 4]triazino[2 3-c]quinazolin-6-il)carboxylates halogen-containing analogues molecular docking anti-inflammatory activity
Online Access:	http://pharmed.zsmu.edu.ua/article/view/62036/58068
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Actoprotective activity of 6-monosubstituted 3-R-6,7-dihydro-2H-[1,2,4]triazino-[2,3-c]quinazoline-2-ones
by: O. S. Kolomoets, et al.
Published: (2016-12-01)

The study of UV-spectra of the sodium (3-oxo-3,4-dihydro-2H-[1,2,4]triazino[4,3-c]quinazolin-4-yl)acetate
by: О. V. Kryvoshey
Published: (2016-04-01)

Substituted pyrrolo[1,2-a][1,2,4]triazolo-(triazino-)[c]quinazolines - a promising class of lipoxygenase inhibitors
by: V. V. Stavytskyi, et al.
Published: (2020-05-01)

Comparative characteristics of therapeutic action of the sodium salt of 4- (3-methyl-2-oxo-2h- [1, 2, 4] triazino [2, 3-c] quinazolin -6-yl) butyric acid (Compound DSK-38) and diclofenac biochemical blood parameters on adjuvant arthritis model
by: V. V. Grib, et al.
Published: (2015-10-01)

Study of the mechanisms cardioprotektive effect of 3-(2,2,2- trimethylhydrazinium) propionate
by: L. M. Danilenko, et al.
Published: (2016-02-01)

METHOD OF PREPARATIVE SYNTHESIS OF 8-OXO-2'-DEOXYGUANOSINE FOR LABORATORY USING
by: N. V. Marmiy, et al.
Published: (2017-08-01)

The аntitumor effect of 2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propanediol (chlonisol) on the growth of spontaneous mammary tumors in HER-2/neu transgenic mice
by: V. A. Alexandrov, et al.
Published: (2023-06-01)

Assessment of Acute Toxicity of Quinazoline Derivative 3-[2-oxo-2-(4-Phenylpiperazine-1-yl)Ethyl]quinazoline-4(3h)-oh Active against Opportunistic Microorganisms
by: N. M. Gabitova, et al.
Published: (2023-07-01)

Synthesis and transformation in the series of 2-((5-(2,4- and 3,4-dimethoxyphenyl)-3H-1,2,4-triazole-3-yl)thio)acetic acids
by: D. V. Dovbnia, et al.
Published: (2021-03-01)

Mastering 1-2-3 /
by: Jorgensen, Carolyn
Published: (1986)

Synthesis of 4,4′,4″-(((Benzene-1,2,3-triyltris(oxy))tris(2-oxoethane-2,1-diyl))tris(oxy))tris(2,3-dihydroxy-4-oxobutanoic Acid) and 4,4′,4″-(((Benzene-1,2,4-triyltris(oxy))tris(2-oxoethane-2,1-diyl))tris(oxy))tris(2,3-dihydroxy-4-oxobutanoic Acid)
by: Ruzimurod Sattorovich Jurayev
Published: (2024-11-01)

2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propanediol (chlonisol): blood content in rats after intravenous administration and chemical resistance
by: V. A. Alexandrov, et al.
Published: (2025-01-01)

Synthesis of 3-[2-(1H-imidazol-2-yl)alkyl]-2-thioxo-2,3-dihydroquinazolin-4(1H)-one derivatives
by: O. A. Zavada, et al.
Published: (2018-10-01)

All about 1-2-3 /
by: Schware, Robert, 1952-
Published: (1983)

1,3-Dipolar Cycloaddition Reactions of 2-Arylmethylidentiazolo[3,2-<i>a</i>]pyrimidines with Azomethinylides: Studying the Supramolecular Organization of Products in the Crystalline Phase
by: Anna Nefedova, et al.
Published: (2024-11-01)

Directed synthesis and search of pharmaceutical substances with hypoglycemic activity in the series of 4-aryl-2-hydroxy-4-oxo-2-butenoic acids
by: N. A. Pulina, et al.
Published: (2011-10-01)

Anticonvulsant activity 2-((5-(3-(4-fluorophenyl)-4-R2-1,2,4-triazole-3-yl)-thio)-1-arylethanone
by: O. A. Bihdan
Published: (2019-12-01)

Physical and chemical properties of some 4-amino-5-(furan-2-, 2-metylfuran-3-yl)-1,2,4-triazole-3-thiol alkyl derivatives
by: D. M. Danilchenko, et al.
Published: (2016-04-01)

8-Oxo-2’-deoxyguanosine – biomarker of the oxidative stress
by: T. S. Nevredimova, et al.
Published: (2014-10-01)

Impact of varying Bi2O3 content on physical, mechanical, structural and gamma ray shielding properties of Bi2O3-B2O3-SiO2-Na2O glass system
by: Aljawhara H. Almuqrin, et al.
Published: (2025-10-01)

The long noncoding RNA lnc-H3f3b2 regulates cow barn PM2.5-induced apoptosis of rat alveolar Ⅱ epithelial cells through a ceRNA mechanism
by: Yize Sun, et al.
Published: (2025-09-01)

DEVELOPMENT OF OPTIMAL PARAMETERS FOR NEW DERIVANTS DETERMINATION OF 4-(GET)ARYL-2-HYDROXY-4-OXO-2-BUTENIC ACIDS IN THIN LAYER OF SORBENT
by: F. V. Sobin, et al.
Published: (2015-09-01)

The student edition of Lotus 1-2-3, Release 2.3 /
by: O'Leary, Timothy J.
Published: (1992)

NOD2-NLRP3 Axis and Asthma
by: Cai X
Published: (2025-05-01)

Penurunan Kadar Metilen Biru Dalam Limbah Batik Sokaraja Menggunakan Sistem Fe2O3-H2O2-UV
by: Dian Windy Dwiasi, et al.
Published: (2018-06-01)

2,2,3,3,4,4,4-Heptafluorobutyl Acetate: Transesterification Reaction of 2,2,3,3,4,4,4-Heptafluoro-1-Butanol and Isopropyl Acetate—Side-Product Composition
by: Andrei V. Polkovnichenko, et al.
Published: (2024-09-01)

Synthesis and Characterization of some bis 1,3-Oxazepine and 2,3-Dihydroquinozoline derivatives
by: Salwa Abdul Sattar Jabbar, et al.
Published: (2023-02-01)

Some aspects of synthesis of new 2-((5-furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-ylthio)acetic acid esters
by: D. M. Danilchenko
Published: (2016-12-01)

Study of the Anti-inflammatory Activity of 2-hydroxy-4-oxo-4-R-2-butenoates of Heterylammonium, which Have an Effect on the Blood Clotting System
by: F. V. Sobin, et al.
Published: (2023-12-01)

Transamination of 3-[(Dimethylamino)methylidene]-5-arylfuran-2(3<i>H</i>)-thiones with the Participation of 1,2-Phenylenediamine
by: Alexandra S. Tikhomolova, et al.
Published: (2024-11-01)

Physical-chemical properties of 2-((5-(3-,4-fluorophenyl)-4-R2-1,2,4-triazol-3-il)tio)-1-arylethanons and their reduced systems
by: O. A. Bihdan
Published: (2019-07-01)

A Systematic Review of Synthetic and Anticancer and Antimicrobial Activity of Quinazoline/Quinazolin‐4‐one Analogues
by: Neha Manhas, et al.
Published: (2025-07-01)

Using Lotus 1-2-3 to solve your business problems
by: Gershefski, George W.
Published: (1984)

Study of Antifungal Activity of Experimental Soft Dosage Form Based on the Hydrazone Derivative of Getarylamide 4-phenyl-2-hydroxy-4-oxo-2-butenoic acid
by: F. V. Sobin, et al.
Published: (2022-12-01)

Using 1-2-3 /
Published: (1987)

1-2-3 release 2.2 : the complete reference /
by: Campbell, Mary V.
Published: (1990)

ANALGETIC ACTIVITY OF SUBSTITUTED 1-(2-IMIDAZOLETHYL)-3- PYRROLINE-2-ONS
by: A. A. Ponomaryova, et al.
Published: (2015-09-01)

1-2-3 release 2.3 made easy /
by: Campbell, Mary
Published: (1991)

Catalytic decomposition of methane over Fe2O3-Al2O3 catalysts with high iron contents and at high CH4 space velocities
by: Shuang Li, et al.
Published: (2025-12-01)

Lotus 1-2-3 release 2, ASAP : a self-teaching guide /
by: Williams, Andrew T., 1943-
Published: (1986)