Current Approaches to PANS/PANDAS Diagnostics and Management

PANS, or Pediatric Acute-onset Neuropsychiatric Syndrome, is characterized by the sudden onset of obsessive-compulsive syndrome and accompanied by anxiety, emotional lability and other symptoms. PANDAS, or Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infections, is a...

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Main Authors: Inna A. Kostik, Mikhail M. Kostik
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2020-01-01
Series:Вопросы современной педиатрии
Subjects:
Online Access:https://vsp.spr-journal.ru/jour/article/view/2230
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author Inna A. Kostik
Mikhail M. Kostik
author_facet Inna A. Kostik
Mikhail M. Kostik
author_sort Inna A. Kostik
collection DOAJ
description PANS, or Pediatric Acute-onset Neuropsychiatric Syndrome, is characterized by the sudden onset of obsessive-compulsive syndrome and accompanied by anxiety, emotional lability and other symptoms. PANDAS, or Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infections, is a subtype of PANS. Modern data on PANS/PANDAS etiology, pathogenesis, diagnostics and management is presented in this article. Therapeutic decisions on using anti-inflammatory and immunotropic therapy including non-steroidal anti-inflammatory drugs, glucocorticoids, intravenous immunoglobulin, plasmapheresis, rituximab and mycophenolate mofetil are analysed.
format Article
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publisher "Paediatrician" Publishers LLC
record_format Article
series Вопросы современной педиатрии
spelling doaj-art-c72d9747734e4b4e8d5247750a48a00c2025-08-04T13:09:40Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352020-01-0118532433810.15690/vsp.v18i5.20551834Current Approaches to PANS/PANDAS Diagnostics and ManagementInna A. Kostik0Mikhail M. Kostik1Children's Sanatorium-Rehabilitation Centre Detskye DunySt. Petersburg State Pediatric Medical University; Almazov National Medical Research CenterPANS, or Pediatric Acute-onset Neuropsychiatric Syndrome, is characterized by the sudden onset of obsessive-compulsive syndrome and accompanied by anxiety, emotional lability and other symptoms. PANDAS, or Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infections, is a subtype of PANS. Modern data on PANS/PANDAS etiology, pathogenesis, diagnostics and management is presented in this article. Therapeutic decisions on using anti-inflammatory and immunotropic therapy including non-steroidal anti-inflammatory drugs, glucocorticoids, intravenous immunoglobulin, plasmapheresis, rituximab and mycophenolate mofetil are analysed.https://vsp.spr-journal.ru/jour/article/view/2230childrenpandaspanscanspitandobsessive-compulsive syndrometichyperkinesisstreptococcusetiologydiagnosticsmanagement
spellingShingle Inna A. Kostik
Mikhail M. Kostik
Current Approaches to PANS/PANDAS Diagnostics and Management
Вопросы современной педиатрии
children
pandas
pans
cans
pitand
obsessive-compulsive syndrome
tic
hyperkinesis
streptococcus
etiology
diagnostics
management
title Current Approaches to PANS/PANDAS Diagnostics and Management
title_full Current Approaches to PANS/PANDAS Diagnostics and Management
title_fullStr Current Approaches to PANS/PANDAS Diagnostics and Management
title_full_unstemmed Current Approaches to PANS/PANDAS Diagnostics and Management
title_short Current Approaches to PANS/PANDAS Diagnostics and Management
title_sort current approaches to pans pandas diagnostics and management
topic children
pandas
pans
cans
pitand
obsessive-compulsive syndrome
tic
hyperkinesis
streptococcus
etiology
diagnostics
management
url https://vsp.spr-journal.ru/jour/article/view/2230
work_keys_str_mv AT innaakostik currentapproachestopanspandasdiagnosticsandmanagement
AT mikhailmkostik currentapproachestopanspandasdiagnosticsandmanagement