The acantamoeba lesions of the cornea (diagnosis) (Review of literature)

The Aсanthamoeba keratitis is a rare, but very dangerous disease of cornea; its development is connected with contact lens wearing, and corneal microtraumas with contamination of particles of the soil or water. The disease has no pronounced distinguishing clinical signs therefore it is difficult to...

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Main Authors: A. A. Kasparov, N. R. Marchenko, E. A. Kasparova
Format: Article
Language:Russian
Published: Journal Infectology 2020-03-01
Series:Журнал инфектологии
Subjects:
Online Access:https://journal.niidi.ru/jofin/article/view/1008
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author A. A. Kasparov
N. R. Marchenko
E. A. Kasparova
author_facet A. A. Kasparov
N. R. Marchenko
E. A. Kasparova
author_sort A. A. Kasparov
collection DOAJ
description The Aсanthamoeba keratitis is a rare, but very dangerous disease of cornea; its development is connected with contact lens wearing, and corneal microtraumas with contamination of particles of the soil or water. The disease has no pronounced distinguishing clinical signs therefore it is difficult to distinguish them from herpetic or fungal keratitis. Nevertheless, it can be suspected on the basis of anamnestic data (use of contact lenses, corneal injury with contamination by the soil or water), uneven strong pain syndrome, ring-shaped infiltration of cornea, absence of effect of traditional therapy. Isolation of Acanthamoeba by bioculture method, morphological research of corneal bioptat (by light and luminescent microscopy), gene diagnostics, in – vivo confocal microscopy of the cornea can give additional help in the diagnosis. Also perspective diagnostic methods of Acanthamoeba keratitis are given. Nevertheless, so far there is no conventional technique of diagnosis of this disease.
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publishDate 2020-03-01
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series Журнал инфектологии
spelling doaj-art-c6b9ec16ab1a43f9a2e621dff162145c2025-08-04T14:25:45ZrusJournal InfectologyЖурнал инфектологии2072-67322020-03-01121142210.22625/2072-6732-2020-12-1-14-22782The acantamoeba lesions of the cornea (diagnosis) (Review of literature)A. A. Kasparov0N. R. Marchenko1E. A. Kasparova2Research Institute of Eye Diseases, Moscow,Research Institute of Eye Diseases, Moscow,Research Institute of Eye DiseasesThe Aсanthamoeba keratitis is a rare, but very dangerous disease of cornea; its development is connected with contact lens wearing, and corneal microtraumas with contamination of particles of the soil or water. The disease has no pronounced distinguishing clinical signs therefore it is difficult to distinguish them from herpetic or fungal keratitis. Nevertheless, it can be suspected on the basis of anamnestic data (use of contact lenses, corneal injury with contamination by the soil or water), uneven strong pain syndrome, ring-shaped infiltration of cornea, absence of effect of traditional therapy. Isolation of Acanthamoeba by bioculture method, morphological research of corneal bioptat (by light and luminescent microscopy), gene diagnostics, in – vivo confocal microscopy of the cornea can give additional help in the diagnosis. Also perspective diagnostic methods of Acanthamoeba keratitis are given. Nevertheless, so far there is no conventional technique of diagnosis of this disease.https://journal.niidi.ru/jofin/article/view/1008acanthamoebaacanthamoeba keratitiscontact lensesconfocal microscopypolimerase chain reaction
spellingShingle A. A. Kasparov
N. R. Marchenko
E. A. Kasparova
The acantamoeba lesions of the cornea (diagnosis) (Review of literature)
Журнал инфектологии
acanthamoeba
acanthamoeba keratitis
contact lenses
confocal microscopy
polimerase chain reaction
title The acantamoeba lesions of the cornea (diagnosis) (Review of literature)
title_full The acantamoeba lesions of the cornea (diagnosis) (Review of literature)
title_fullStr The acantamoeba lesions of the cornea (diagnosis) (Review of literature)
title_full_unstemmed The acantamoeba lesions of the cornea (diagnosis) (Review of literature)
title_short The acantamoeba lesions of the cornea (diagnosis) (Review of literature)
title_sort acantamoeba lesions of the cornea diagnosis review of literature
topic acanthamoeba
acanthamoeba keratitis
contact lenses
confocal microscopy
polimerase chain reaction
url https://journal.niidi.ru/jofin/article/view/1008
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