IgE clonality and aggregation of insulin affect IgE-mediated activation of sensitized basophils

IgE clonality and aggregation of insulin affect IgE-mediated activation of sensitized basophils

Background: Skin prick testing and specific IgE determination do not discriminate between sensitization and clinically relevant insulin allergic reactions, whereas the basophil histamine release assay has proven useful in identifying clinically relevant food and drug allergic reactions. Objective: W...

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Bibliographic Details
Main Authors: Steffen Christoffersen, MSc, Katrine Baumann, PhD, Anders Holm Millner, PhD, Henrik Toft-Hansen, PhD, Eva Johansson, PhD, Camilla Thorlaksen, PhD, Per Stahl Skov, PhD
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Journal of Allergy and Clinical Immunology: Global
Subjects:
Insulin
insulin allergy
drug allergy
allergy
BHRA
basophil histamine release assay
Online Access:http://www.sciencedirect.com/science/article/pii/S2772829325001031
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