Variability of response to pharmacotherapy of naltrexone and guanfacin in patients with opioid dependence syndrome: pharmacogenetic aspect

Variability of response to pharmacotherapy of naltrexone and guanfacin in patients with opioid dependence syndrome: pharmacogenetic aspect

There is a problem of insufficient effectiveness of pharmacotherapy for the relapse prevention in patients with opioid dependence. In Russian Federation naltrexone is a mainly used medication for treatment of opioid addiction. However, it has no effects on stress, craving, and impulsiveness. Alpha-2...

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Bibliographic Details
Main Authors: V. Ya Palatkin, A. O. Kibitov, Е. M. Krupitsky, Е. A. Blokhina Е.A., V. M Brodyansky, Е. V. Verbitskaya, E. E. Zvartau
Format: Article
Language:Russian
Published: Federal State Budget Scientific Institution National Medical Research Center for Psychiatry and Neurology n.a. V.M. Bekhterev Ministry of Health of the Russian Federation 2019-12-01
Series:Обозрение психиатрии и медицинской психологии имени В.М. Бехтерева
Subjects:
opioid addiction, remission, remission stabilization, naltrexone, guanfacin, pharmacogenetics
Online Access:https://www.bekhterevreview.com/jour/article/view/329
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