A 3D Composite Model Using Electrospinning Technology to Study Endothelial Damage

A 3D Composite Model Using Electrospinning Technology to Study Endothelial Damage

Background: Endothelial dysfunction triggers atherosclerosis pathogenesis. This study aimed at developing a 3D scaffold model able to reproduce in vitro the human vascular intima and study the endothelial damage induced by oxidative low-density lipoproteins (ox-LDLs) and shear stress. (2) Methods: T...

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Bibliographic Details
Main Authors: Carmen Ciavarella, Luana Di Lisa, Gianandrea Pasquinelli, Maria Letizia Focarete, Sabrina Valente
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomolecules
Subjects:
electrospun scaffolds
endothelial dysfunction
oxidized LDL
shear stress
bioreactor
Online Access:https://www.mdpi.com/2218-273X/15/6/865
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