BRAFV600E mutation and its association with clinicopathological features of colorectal cancer: a systematic review and meta-analysis.

<h4>Background</h4>Colorectal cancer (CRC) is a heterogeneous disease with multiple underlying causative genetic mutations. The B-type Raf proto-oncogene (BRAF) plays an important role in the mitogen-activated protein kinase (MAPK) signaling cascade during CRC. The presence of BRAFV600E...

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Bibliographic Details
Main Authors: Dong Chen, Jun-Fu Huang, Kai Liu, Li-Qun Zhang, Zhao Yang, Zheng-Ran Chuai, Yun-Xia Wang, Da-Chuan Shi, Qing Huang, Wei-Ling Fu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090607&type=printable
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