Natural mutations in key NLS amino acids regulate nucleoplasmic shuttling and replication efficiency in PRRSV
Highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) is a mutant strain of the classic porcine reproductive and respiratory syndrome virus (PRRSV) characterized by high morbidity and mortality rates. Epidemiological analysis revealed a natural mutation and stable inherita...
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Main Authors: | Xianchang Zhu, Yang Xia, Qian Lei, Yu Gan, Shenghai Jiang, Lian Huang, Qihu Wen, Wei Fu, Bo Zhang, Yi Zhang, Shanshan Xie, Jida Li |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2025-07-01
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Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fmicb.2025.1587634/full |
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