The pathomorphological characteristics of clear-cell adenocarcinomas of the ovary and its mixed tumors with a clear-cell component

Objective: to study the pathomorphological signs of pure and mixed clear-cell ovarian tumors with a clear-cell component.Subjects and methods. The clinical and morphological characteristics and the course of the disease were analyzed in 96 patients aged 21 to 75 years with clear-cell ovarian carcino...

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Main Authors: M.. D Akhmedova, M. A. Shabanov, V. V. Barinov, K. I. Zhordania, L. I. Bokina, E. A. Mustafina
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Опухоли женской репродуктивной системы
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Online Access:https://ojrs.abvpress.ru/ojrs/article/view/146
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author M.. D Akhmedova
M. A. Shabanov
V. V. Barinov
K. I. Zhordania
L. I. Bokina
E. A. Mustafina
author_facet M.. D Akhmedova
M. A. Shabanov
V. V. Barinov
K. I. Zhordania
L. I. Bokina
E. A. Mustafina
author_sort M.. D Akhmedova
collection DOAJ
description Objective: to study the pathomorphological signs of pure and mixed clear-cell ovarian tumors with a clear-cell component.Subjects and methods. The clinical and morphological characteristics and the course of the disease were analyzed in 96 patients aged 21 to 75 years with clear-cell ovarian carcinoma. All the patients were divided into 2 groups: 1) 71 patients with pure clear-cell ovarian adenocarcinomas (COA) and 2) 25 patients with mixed malignant ovarian epithelial tumors (MMOET) with an obligatory clear-cell component. All pure forms of ovarian clear-cell malignancies were represented by adenocarcinoma in our study. This histologic type of the tumor was also prevalent among mixed ovarian neoplasms.Results. Clear, optically transparent cells and shoe nail-type (nail) ones were most common in COA. MMOETs showed moderate dif- ferentiation and malignancy and moderate atypia of a cell. Pure clear-cell neoplasms generally displayed 3 to 6 mitoses in 10 fields of vision whereas MMOET exhibited as many as 3 mitoses in 10 fields of vision.
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institution Matheson Library
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language Russian
publishDate 2014-07-01
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record_format Article
series Опухоли женской репродуктивной системы
spelling doaj-art-c2d9a6437c5e43e29538d55ece4c8ebe2025-08-04T14:33:37ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-07-0101707510.17650/1994-4098-2011-0-1-70-75162The pathomorphological characteristics of clear-cell adenocarcinomas of the ovary and its mixed tumors with a clear-cell componentM.. D Akhmedova0M. A. Shabanov1V. V. Barinov2K. I. Zhordania3L. I. Bokina4E. A. Mustafina5N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowObjective: to study the pathomorphological signs of pure and mixed clear-cell ovarian tumors with a clear-cell component.Subjects and methods. The clinical and morphological characteristics and the course of the disease were analyzed in 96 patients aged 21 to 75 years with clear-cell ovarian carcinoma. All the patients were divided into 2 groups: 1) 71 patients with pure clear-cell ovarian adenocarcinomas (COA) and 2) 25 patients with mixed malignant ovarian epithelial tumors (MMOET) with an obligatory clear-cell component. All pure forms of ovarian clear-cell malignancies were represented by adenocarcinoma in our study. This histologic type of the tumor was also prevalent among mixed ovarian neoplasms.Results. Clear, optically transparent cells and shoe nail-type (nail) ones were most common in COA. MMOETs showed moderate dif- ferentiation and malignancy and moderate atypia of a cell. Pure clear-cell neoplasms generally displayed 3 to 6 mitoses in 10 fields of vision whereas MMOET exhibited as many as 3 mitoses in 10 fields of vision.https://ojrs.abvpress.ru/ojrs/article/view/146clear-cell ovarian adenocarcinomasmixed malignant ovarian epithelial tumors with a clear-cell componentclinical and morphological signs
spellingShingle M.. D Akhmedova
M. A. Shabanov
V. V. Barinov
K. I. Zhordania
L. I. Bokina
E. A. Mustafina
The pathomorphological characteristics of clear-cell adenocarcinomas of the ovary and its mixed tumors with a clear-cell component
Опухоли женской репродуктивной системы
clear-cell ovarian adenocarcinomas
mixed malignant ovarian epithelial tumors with a clear-cell component
clinical and morphological signs
title The pathomorphological characteristics of clear-cell adenocarcinomas of the ovary and its mixed tumors with a clear-cell component
title_full The pathomorphological characteristics of clear-cell adenocarcinomas of the ovary and its mixed tumors with a clear-cell component
title_fullStr The pathomorphological characteristics of clear-cell adenocarcinomas of the ovary and its mixed tumors with a clear-cell component
title_full_unstemmed The pathomorphological characteristics of clear-cell adenocarcinomas of the ovary and its mixed tumors with a clear-cell component
title_short The pathomorphological characteristics of clear-cell adenocarcinomas of the ovary and its mixed tumors with a clear-cell component
title_sort pathomorphological characteristics of clear cell adenocarcinomas of the ovary and its mixed tumors with a clear cell component
topic clear-cell ovarian adenocarcinomas
mixed malignant ovarian epithelial tumors with a clear-cell component
clinical and morphological signs
url https://ojrs.abvpress.ru/ojrs/article/view/146
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