The pathomorphological characteristics of clear-cell adenocarcinomas of the ovary and its mixed tumors with a clear-cell component
Objective: to study the pathomorphological signs of pure and mixed clear-cell ovarian tumors with a clear-cell component.Subjects and methods. The clinical and morphological characteristics and the course of the disease were analyzed in 96 patients aged 21 to 75 years with clear-cell ovarian carcino...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
ABV-press
2014-07-01
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| Series: | Опухоли женской репродуктивной системы |
| Subjects: | |
| Online Access: | https://ojrs.abvpress.ru/ojrs/article/view/146 |
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| Summary: | Objective: to study the pathomorphological signs of pure and mixed clear-cell ovarian tumors with a clear-cell component.Subjects and methods. The clinical and morphological characteristics and the course of the disease were analyzed in 96 patients aged 21 to 75 years with clear-cell ovarian carcinoma. All the patients were divided into 2 groups: 1) 71 patients with pure clear-cell ovarian adenocarcinomas (COA) and 2) 25 patients with mixed malignant ovarian epithelial tumors (MMOET) with an obligatory clear-cell component. All pure forms of ovarian clear-cell malignancies were represented by adenocarcinoma in our study. This histologic type of the tumor was also prevalent among mixed ovarian neoplasms.Results. Clear, optically transparent cells and shoe nail-type (nail) ones were most common in COA. MMOETs showed moderate dif- ferentiation and malignancy and moderate atypia of a cell. Pure clear-cell neoplasms generally displayed 3 to 6 mitoses in 10 fields of vision whereas MMOET exhibited as many as 3 mitoses in 10 fields of vision. |
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| ISSN: | 1994-4098 1999-8627 |