Effect of the Ketoprofen Distribution in Cream-gels on the Formation of the Impurities
Introduction. The fixed combination of ketoprofen, methyl salicylate and levomenthol in the form of a cream-gel is rational. Ketoprofen forms salts with bases and esters with substances containing hydroxyl groups. Ketoprofen is practically insoluble in water, and the solubility of ketoprofen salts i...
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Main Authors: | N. A. Lyapunov, I. A. Zinchenko, E. P. Bezuglaya, A. A. Lysokobilka |
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Format: | Article |
Language: | Russian |
Published: |
LLC Center of Pharmaceutical Analytics (LLC «CPHA»)
2019-05-01
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Series: | Разработка и регистрация лекарственных средств |
Subjects: | |
Online Access: | https://www.pharmjournal.ru/jour/article/view/682 |
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