Helminths and intestinal microbiota interaction: role in the development of noncommunicable diseases
There is an increase in the prevalence of chronic, noncommunicable diseases, including allergic and autoimmune diseases in developed countries. In this regard, the study of factors modifying the population’s immune response is very important.According to the “old friends” hypothesis , insufficiency...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2019-10-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/2419 |
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| author | T. S. Sokolova O. S. Fedorova I. V. Saltykova V. A. Petrov M. M. Fedotova Yu. V. Kovshirina I. A. Deev L. M. Ogorodova |
| author_facet | T. S. Sokolova O. S. Fedorova I. V. Saltykova V. A. Petrov M. M. Fedotova Yu. V. Kovshirina I. A. Deev L. M. Ogorodova |
| author_sort | T. S. Sokolova |
| collection | DOAJ |
| description | There is an increase in the prevalence of chronic, noncommunicable diseases, including allergic and autoimmune diseases in developed countries. In this regard, the study of factors modifying the population’s immune response is very important.According to the “old friends” hypothesis , insufficiency of infectious stimulation and decrease in prevalence of helminthiasis are associated with development of noncommunicable diseases. Studies revealed that intestinal parasites modulate the host immune response and alter susceptibility to immunological diseases. It is suggested that one of the pathogenetic mechanisms of immune response modulation by parasites is an increase in the content of gastrointestinal bacteria with anti-inflammatory effect. Advanced technologies of microorganism identification provide a deep insight into the microbiota in different pathologies. The study of changes in the intestine and bile microbiota of the host in helminthiases provides new possibilities for prevention, diagnosis and control of such conditions as chronic inflammatory bowel diseases and allergic diseases. The purpose of this review is to analyze current experimental and clinical data on intestinal microbiota in helminth infections and possible association with development of chronic noncommunicable diseases. |
| format | Article |
| id | doaj-art-c29418bc97ec4d62a042e0ba0ec4d5e7 |
| institution | Matheson Library |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2019-10-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-c29418bc97ec4d62a042e0ba0ec4d5e72025-08-04T16:45:41ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842019-10-0118321422510.20538/1682-0363-2019-3-214-2251555Helminths and intestinal microbiota interaction: role in the development of noncommunicable diseasesT. S. Sokolova0O. S. Fedorova1I. V. Saltykova2V. A. Petrov3M. M. Fedotova4Yu. V. Kovshirina5I. A. Deev6L. M. Ogorodova7Siberian State Medical University (SSMU)Siberian State Medical University (SSMU)Siberian State Medical University (SSMU)Siberian State Medical University (SSMU)Siberian State Medical University (SSMU)Siberian State Medical University (SSMU)Siberian State Medical University (SSMU)Siberian State Medical University (SSMU)There is an increase in the prevalence of chronic, noncommunicable diseases, including allergic and autoimmune diseases in developed countries. In this regard, the study of factors modifying the population’s immune response is very important.According to the “old friends” hypothesis , insufficiency of infectious stimulation and decrease in prevalence of helminthiasis are associated with development of noncommunicable diseases. Studies revealed that intestinal parasites modulate the host immune response and alter susceptibility to immunological diseases. It is suggested that one of the pathogenetic mechanisms of immune response modulation by parasites is an increase in the content of gastrointestinal bacteria with anti-inflammatory effect. Advanced technologies of microorganism identification provide a deep insight into the microbiota in different pathologies. The study of changes in the intestine and bile microbiota of the host in helminthiases provides new possibilities for prevention, diagnosis and control of such conditions as chronic inflammatory bowel diseases and allergic diseases. The purpose of this review is to analyze current experimental and clinical data on intestinal microbiota in helminth infections and possible association with development of chronic noncommunicable diseases.https://bulletin.ssmu.ru/jour/article/view/2419microbiomeintestinal microbiotahelminthiasisopisthorchis felineuschronic noncommunicable diseases |
| spellingShingle | T. S. Sokolova O. S. Fedorova I. V. Saltykova V. A. Petrov M. M. Fedotova Yu. V. Kovshirina I. A. Deev L. M. Ogorodova Helminths and intestinal microbiota interaction: role in the development of noncommunicable diseases Бюллетень сибирской медицины microbiome intestinal microbiota helminthiasis opisthorchis felineus chronic noncommunicable diseases |
| title | Helminths and intestinal microbiota interaction: role in the development of noncommunicable diseases |
| title_full | Helminths and intestinal microbiota interaction: role in the development of noncommunicable diseases |
| title_fullStr | Helminths and intestinal microbiota interaction: role in the development of noncommunicable diseases |
| title_full_unstemmed | Helminths and intestinal microbiota interaction: role in the development of noncommunicable diseases |
| title_short | Helminths and intestinal microbiota interaction: role in the development of noncommunicable diseases |
| title_sort | helminths and intestinal microbiota interaction role in the development of noncommunicable diseases |
| topic | microbiome intestinal microbiota helminthiasis opisthorchis felineus chronic noncommunicable diseases |
| url | https://bulletin.ssmu.ru/jour/article/view/2419 |
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