DYNAMIC EVALUATION CONDITION OF RENAL PARENCHYMA IN PATIENTS AFTER EXTERNAL SHOCK WAVE LITHOTRIPSY OF KIDNEY STONES

The study includes the results of treatment of 167 patients with nephrolithiasis: first group included 80 patients with 1 session of extracorporeal shock wave lithotripsy (ESWL), the second group consisted of 87 patients who underwent 2-4 session ESWL. All patients underwent duplex scanning in renal...

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Main Authors: A. N. Rossolovsky, M. L. Chekhonatskaya, N. B. Zakharova, O. L. Berezinets, N. V. Emelyanova
Format: Article
Language:Russian
Published: Ministry of Health of Russian Federation, Rostov State Medical University, State Budget Educational Institute of Higher Professional Education 2014-06-01
Series:Вестник урологии
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Online Access:https://www.urovest.ru/jour/article/view/54
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author A. N. Rossolovsky
M. L. Chekhonatskaya
N. B. Zakharova
O. L. Berezinets
N. V. Emelyanova
author_facet A. N. Rossolovsky
M. L. Chekhonatskaya
N. B. Zakharova
O. L. Berezinets
N. V. Emelyanova
author_sort A. N. Rossolovsky
collection DOAJ
description The study includes the results of treatment of 167 patients with nephrolithiasis: first group included 80 patients with 1 session of extracorporeal shock wave lithotripsy (ESWL), the second group consisted of 87 patients who underwent 2-4 session ESWL. All patients underwent duplex scanning in renal blood flow, was determined by the concentration of serum creatinine and estimate the glomerular filtration rate. ELISA also investigated the dynamics of the content of lipocalin-2 (NGAL) and β2-microglobulin. All studies were performed at 5-7, 10-14, and 1-3 months after treatment. It is shown that in case of ESWL occurs renal parenchymal damage of varying degree, aggravated by increasing the number of sessions. By the early markers of acute kidney injury in patients with nephrolithiasis should include an increase urinary excretion of β2-MG and NGAL. Results of dynamic duplex scanning can reveal the underlying mechanisms of progression of renal dysfunction in patients after ESWL.
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language Russian
publishDate 2014-06-01
publisher Ministry of Health of Russian Federation, Rostov State Medical University, State Budget Educational Institute of Higher Professional Education
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series Вестник урологии
spelling doaj-art-c25d052335b4414c99ae06b5124ef5b52025-08-04T12:51:12ZrusMinistry of Health of Russian Federation, Rostov State Medical University, State Budget Educational Institute of Higher Professional EducationВестник урологии2308-64242014-06-010231410.21886/2308-6424-2014-0-2-3-1453DYNAMIC EVALUATION CONDITION OF RENAL PARENCHYMA IN PATIENTS AFTER EXTERNAL SHOCK WAVE LITHOTRIPSY OF KIDNEY STONESA. N. Rossolovsky0M. L. Chekhonatskaya1N. B. Zakharova2O. L. Berezinets3N. V. Emelyanova4Research Institute of Fundamental and Clinical Uronephrology Saratov State Medical University named after V.I.Razumovsky, Saratov; Сlinical Hospital named after S.R.Mirotvorsev Saratov State Medical University named after V.I.Razumovsky, SaratovResearch Institute of Fundamental and Clinical Uronephrology Saratov State Medical University named after V.I.Razumovsky, Saratov; Сlinical Hospital named after S.R.Mirotvorsev Saratov State Medical University named after V.I.Razumovsky, SaratovResearch Institute of Fundamental and Clinical Uronephrology Saratov State Medical University named after V.I.Razumovsky, Saratov; Сlinical Hospital named after S.R.Mirotvorsev Saratov State Medical University named after V.I.Razumovsky, SaratovResearch Institute of Fundamental and Clinical Uronephrology Saratov State Medical University named after V.I.Razumovsky, Saratov; Сlinical Hospital named after S.R.Mirotvorsev Saratov State Medical University named after V.I.Razumovsky, SaratovСlinical Hospital named after S.R.Mirotvorsev Saratov State Medical University named after V.I.Razumovsky, SaratovThe study includes the results of treatment of 167 patients with nephrolithiasis: first group included 80 patients with 1 session of extracorporeal shock wave lithotripsy (ESWL), the second group consisted of 87 patients who underwent 2-4 session ESWL. All patients underwent duplex scanning in renal blood flow, was determined by the concentration of serum creatinine and estimate the glomerular filtration rate. ELISA also investigated the dynamics of the content of lipocalin-2 (NGAL) and β2-microglobulin. All studies were performed at 5-7, 10-14, and 1-3 months after treatment. It is shown that in case of ESWL occurs renal parenchymal damage of varying degree, aggravated by increasing the number of sessions. By the early markers of acute kidney injury in patients with nephrolithiasis should include an increase urinary excretion of β2-MG and NGAL. Results of dynamic duplex scanning can reveal the underlying mechanisms of progression of renal dysfunction in patients after ESWL.https://www.urovest.ru/jour/article/view/54nephrolithiasisextracorporeal shock wave lithotripsykidney damage
spellingShingle A. N. Rossolovsky
M. L. Chekhonatskaya
N. B. Zakharova
O. L. Berezinets
N. V. Emelyanova
DYNAMIC EVALUATION CONDITION OF RENAL PARENCHYMA IN PATIENTS AFTER EXTERNAL SHOCK WAVE LITHOTRIPSY OF KIDNEY STONES
Вестник урологии
nephrolithiasis
extracorporeal shock wave lithotripsy
kidney damage
title DYNAMIC EVALUATION CONDITION OF RENAL PARENCHYMA IN PATIENTS AFTER EXTERNAL SHOCK WAVE LITHOTRIPSY OF KIDNEY STONES
title_full DYNAMIC EVALUATION CONDITION OF RENAL PARENCHYMA IN PATIENTS AFTER EXTERNAL SHOCK WAVE LITHOTRIPSY OF KIDNEY STONES
title_fullStr DYNAMIC EVALUATION CONDITION OF RENAL PARENCHYMA IN PATIENTS AFTER EXTERNAL SHOCK WAVE LITHOTRIPSY OF KIDNEY STONES
title_full_unstemmed DYNAMIC EVALUATION CONDITION OF RENAL PARENCHYMA IN PATIENTS AFTER EXTERNAL SHOCK WAVE LITHOTRIPSY OF KIDNEY STONES
title_short DYNAMIC EVALUATION CONDITION OF RENAL PARENCHYMA IN PATIENTS AFTER EXTERNAL SHOCK WAVE LITHOTRIPSY OF KIDNEY STONES
title_sort dynamic evaluation condition of renal parenchyma in patients after external shock wave lithotripsy of kidney stones
topic nephrolithiasis
extracorporeal shock wave lithotripsy
kidney damage
url https://www.urovest.ru/jour/article/view/54
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