IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA
Abstract. Thirty-seven children (7 to 14 years old) with chronic inflammatory lung diseases (ILD) were under study. It was revealed that the contents of T-lymphocytes with CD3+ and CD4+ markers, and B-lymphocytes (CD20+) were relatively decreased in the patients, but their absolute amounts proved to...
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
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| Online Access: | https://www.mimmun.ru/mimmun/article/view/273 |
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| author | B. I. Kuznik B. Ts. Batozghargalova Yu. A. Vitkovsky |
| author_facet | B. I. Kuznik B. Ts. Batozghargalova Yu. A. Vitkovsky |
| author_sort | B. I. Kuznik |
| collection | DOAJ |
| description | Abstract. Thirty-seven children (7 to 14 years old) with chronic inflammatory lung diseases (ILD) were under study. It was revealed that the contents of T-lymphocytes with CD3+ and CD4+ markers, and B-lymphocytes (CD20+) were relatively decreased in the patients, but their absolute amounts proved to be increased, along with sufficiently decreased CD4+/CD8+ ratio, and diminished IgA, IgG and IgM concentrations. The numbers of lymphocyte able to adhere to platelets was relatively decreased, being, however, increased in absolute counts. In the patients with ILD, we have found increased levels of IL-1β, IL-8, TNFα, IFNα, IFNγ. The lymphocyte-to-platelet adherence is an objective test that reflects functional state of cell immunity. (Med. Immunol., vol. 10, N 6, pp 583-588). |
| format | Article |
| id | doaj-art-c22bf0afadbc4aefaa0e5aba622b92fe |
| institution | Matheson Library |
| issn | 1563-0625 2313-741X |
| language | Russian |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj-art-c22bf0afadbc4aefaa0e5aba622b92fe2025-08-04T14:30:29ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0110658358810.15789/1563-0625-2008-6-583-588270IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIAB. I. Kuznik0B. Ts. Batozghargalova1Yu. A. Vitkovsky2ГОУ ВПО Читинская государственная медицинская академия, г. ЧитаГОУ ВПО Читинская государственная медицинская академия, г. ЧитаГОУ ВПО Читинская государственная медицинская академия, г. ЧитаAbstract. Thirty-seven children (7 to 14 years old) with chronic inflammatory lung diseases (ILD) were under study. It was revealed that the contents of T-lymphocytes with CD3+ and CD4+ markers, and B-lymphocytes (CD20+) were relatively decreased in the patients, but their absolute amounts proved to be increased, along with sufficiently decreased CD4+/CD8+ ratio, and diminished IgA, IgG and IgM concentrations. The numbers of lymphocyte able to adhere to platelets was relatively decreased, being, however, increased in absolute counts. In the patients with ILD, we have found increased levels of IL-1β, IL-8, TNFα, IFNα, IFNγ. The lymphocyte-to-platelet adherence is an objective test that reflects functional state of cell immunity. (Med. Immunol., vol. 10, N 6, pp 583-588).https://www.mimmun.ru/mimmun/article/view/273inflammatory lung diseasesimmunitylymphocyte-platelet adhesion |
| spellingShingle | B. I. Kuznik B. Ts. Batozghargalova Yu. A. Vitkovsky IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA Медицинская иммунология inflammatory lung diseases immunity lymphocyte-platelet adhesion |
| title | IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA |
| title_full | IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA |
| title_fullStr | IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA |
| title_full_unstemmed | IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA |
| title_short | IMMUNE STATE AND LYMPHOCYTE-TO-PLATELET ADHESION IN CHILDREN WITH CHRONIC DEFORMING BRONCHITIS AND BRONCHIECTASIA |
| title_sort | immune state and lymphocyte to platelet adhesion in children with chronic deforming bronchitis and bronchiectasia |
| topic | inflammatory lung diseases immunity lymphocyte-platelet adhesion |
| url | https://www.mimmun.ru/mimmun/article/view/273 |
| work_keys_str_mv | AT bikuznik immunestateandlymphocytetoplateletadhesioninchildrenwithchronicdeformingbronchitisandbronchiectasia AT btsbatozghargalova immunestateandlymphocytetoplateletadhesioninchildrenwithchronicdeformingbronchitisandbronchiectasia AT yuavitkovsky immunestateandlymphocytetoplateletadhesioninchildrenwithchronicdeformingbronchitisandbronchiectasia |