Preoperative Nodal Biopsy and Extranodal Extension in p16+ Oropharyngeal Squamous Cell Carcinoma

Preoperative Nodal Biopsy and Extranodal Extension in p16+ Oropharyngeal Squamous Cell Carcinoma

ABSTRACT Objective ENE is an important prognostic factor in p16‐positive OPSCC and is an indication for adjuvant chemoradiation. A recent single institution retrospective study demonstrated that core needle biopsy (CNB) was independently associated with ENE, potentially due to disruption of the lymp...

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Bibliographic Details
Main Authors: Sindhura Sridhar, Daniel P. Larson, Sweeya Raj, Whitney Jin, Vivian L. Zhu, Melanie Hicks, Kyle Mannion, Michael C. Topf
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Laryngoscope Investigative Otolaryngology
Subjects:
extranodal extension
HPV
nodal biopsy
oropharyngeal squamous cell carcinoma
transoral robotic surgery
Online Access:https://doi.org/10.1002/lio2.70150
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