Mitochondrial Pathway Signature (MitoPS) predicts immunotherapy response and reveals NDUFB10 as a key immune regulator in lung adenocarcinoma
Background Lung adenocarcinoma (LUAD) is the most common subtype of non-small cell lung cancer. Although immune checkpoint inhibitors (ICIs) have brought new treatment options for advanced patients, a considerable proportion still shows limited response. Mitochondrial dysfunction plays a crucial rol...
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Main Authors: | Peng Luo, Zhenfa Zhang, Lianmin Zhang, Pengpeng Zhang, Mengzhe Zhang, Jianlan Liu, Zhaokai Zhou |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2025-07-01
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Series: | Journal for ImmunoTherapy of Cancer |
Online Access: | https://jitc.bmj.com/content/13/7/e012069.full |
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