Clinical Presentation and Diagnosis of Multisystemic Eosinophilic Epitheliotropic Disease in a Miniature Donkey: A Case Report

ABSTRACT A 21‐year‐old miniature donkey gelding was evaluated for pruritus, inappetence, hypertriglyceridemia, and alopecia of 2 weeks' duration. Hematology showed moderate eosinophilia, severe hypertriglyceridemia, and moderately increased liver enzyme activities. Cytologic evaluation of perit...

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Main Authors: Carla K. Enriquez, Alicia E. Long, Cristobal Navas deSolis, Perry L. Habecker, Rose Nolen‐Walston
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Journal of Veterinary Internal Medicine
Subjects:
Online Access:https://doi.org/10.1111/jvim.70172
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author Carla K. Enriquez
Alicia E. Long
Cristobal Navas deSolis
Perry L. Habecker
Rose Nolen‐Walston
author_facet Carla K. Enriquez
Alicia E. Long
Cristobal Navas deSolis
Perry L. Habecker
Rose Nolen‐Walston
author_sort Carla K. Enriquez
collection DOAJ
description ABSTRACT A 21‐year‐old miniature donkey gelding was evaluated for pruritus, inappetence, hypertriglyceridemia, and alopecia of 2 weeks' duration. Hematology showed moderate eosinophilia, severe hypertriglyceridemia, and moderately increased liver enzyme activities. Cytologic evaluation of peritoneal fluid identified an eosinophilic transudate. The donkey was treated with antihistamines, anthelmintics, IV fluids with dextrose as a constant rate infusion, and insulin. The miniature donkey was euthanized because of the development of laminitis. Lesions associated with multisystemic eosinophilic epitheliotropic disease (MEED) were identified at necropsy.
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spelling doaj-art-c0b6af8f68cb44648be0bb6ce2bcdebe2025-07-30T05:48:43ZengWileyJournal of Veterinary Internal Medicine0891-66401939-16762025-07-01394n/an/a10.1111/jvim.70172Clinical Presentation and Diagnosis of Multisystemic Eosinophilic Epitheliotropic Disease in a Miniature Donkey: A Case ReportCarla K. Enriquez0Alicia E. Long1Cristobal Navas deSolis2Perry L. Habecker3Rose Nolen‐Walston4Department of Clinical Studies University of Pennsylvania New Bolton Center Hospital for Large Animals Kennett Square Pennsylvania USADepartment of Clinical Studies University of Pennsylvania New Bolton Center Hospital for Large Animals Kennett Square Pennsylvania USADepartment of Clinical Studies University of Pennsylvania New Bolton Center Hospital for Large Animals Kennett Square Pennsylvania USADepartment of Clinical Studies University of Pennsylvania New Bolton Center Hospital for Large Animals Kennett Square Pennsylvania USADepartment of Clinical Studies University of Pennsylvania New Bolton Center Hospital for Large Animals Kennett Square Pennsylvania USAABSTRACT A 21‐year‐old miniature donkey gelding was evaluated for pruritus, inappetence, hypertriglyceridemia, and alopecia of 2 weeks' duration. Hematology showed moderate eosinophilia, severe hypertriglyceridemia, and moderately increased liver enzyme activities. Cytologic evaluation of peritoneal fluid identified an eosinophilic transudate. The donkey was treated with antihistamines, anthelmintics, IV fluids with dextrose as a constant rate infusion, and insulin. The miniature donkey was euthanized because of the development of laminitis. Lesions associated with multisystemic eosinophilic epitheliotropic disease (MEED) were identified at necropsy.https://doi.org/10.1111/jvim.70172eosinophiliaeosinophilic disorderhepatopathyMEEDpruritus
spellingShingle Carla K. Enriquez
Alicia E. Long
Cristobal Navas deSolis
Perry L. Habecker
Rose Nolen‐Walston
Clinical Presentation and Diagnosis of Multisystemic Eosinophilic Epitheliotropic Disease in a Miniature Donkey: A Case Report
Journal of Veterinary Internal Medicine
eosinophilia
eosinophilic disorder
hepatopathy
MEED
pruritus
title Clinical Presentation and Diagnosis of Multisystemic Eosinophilic Epitheliotropic Disease in a Miniature Donkey: A Case Report
title_full Clinical Presentation and Diagnosis of Multisystemic Eosinophilic Epitheliotropic Disease in a Miniature Donkey: A Case Report
title_fullStr Clinical Presentation and Diagnosis of Multisystemic Eosinophilic Epitheliotropic Disease in a Miniature Donkey: A Case Report
title_full_unstemmed Clinical Presentation and Diagnosis of Multisystemic Eosinophilic Epitheliotropic Disease in a Miniature Donkey: A Case Report
title_short Clinical Presentation and Diagnosis of Multisystemic Eosinophilic Epitheliotropic Disease in a Miniature Donkey: A Case Report
title_sort clinical presentation and diagnosis of multisystemic eosinophilic epitheliotropic disease in a miniature donkey a case report
topic eosinophilia
eosinophilic disorder
hepatopathy
MEED
pruritus
url https://doi.org/10.1111/jvim.70172
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AT cristobalnavasdesolis clinicalpresentationanddiagnosisofmultisystemiceosinophilicepitheliotropicdiseaseinaminiaturedonkeyacasereport
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