Transjugular intrahepatic portocaval shunting as a preparation phase for liver transplantation
Objective: to assess the first results of transjugular intrahepatic portocaval shunting (TIPS) as a technique for preventing portal hypertension complications in patients in the period of waiting for a donor liver.Subjects and methods. TIPS was performed in 6 patients on the list of waiting for orth...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
2018-08-01
|
| Series: | Трансплантология (Москва) |
| Subjects: | |
| Online Access: | https://www.jtransplantologiya.ru/jour/article/view/238 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1839579916100698112 |
|---|---|
| author | P. G. Tarazov D. A. Granov A. A. Polikarpov M. I. Generalov I. O. Rutkin O. A. Gerasimova F. K. Zherebtsov |
| author_facet | P. G. Tarazov D. A. Granov A. A. Polikarpov M. I. Generalov I. O. Rutkin O. A. Gerasimova F. K. Zherebtsov |
| author_sort | P. G. Tarazov |
| collection | DOAJ |
| description | Objective: to assess the first results of transjugular intrahepatic portocaval shunting (TIPS) as a technique for preventing portal hypertension complications in patients in the period of waiting for a donor liver.Subjects and methods. TIPS was performed in 6 patients on the list of waiting for orthotopic liver transplantation (OLT). The indications for TIPS were current (n=1) or high-risk recurrent hemorrhages from the esophageal varices and stomach (n=4) and diuretic-resistant ascitis (n=1).Results. TIPS was successfully carried out in all the patients. The portovenous gradient was reduced by 2—3 times (to 9—12 mm Hg). A further follow-up revealed recurrent varicose hemorrhage or ascitis in none patients. Doppler study indicated that the shunt showed a good function. OLT was successfully made in 3 patients 2, 8, and 19 months after TIPS; one female patient had been waiting for OLT for 5 months; 2 patients died from sepsis and hepatic failure following 1 and 5 months, respectively.Conclusion. The first results suggest that in patients with hepatic cirrhosis complicated with portal hypertension, TIPS can be regarded as a safety bridge while waiting for a donor liver. |
| format | Article |
| id | doaj-art-c0a87505d1cb4150b6cf81d73867202f |
| institution | Matheson Library |
| issn | 2074-0506 2542-0909 |
| language | English |
| publishDate | 2018-08-01 |
| publisher | N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department |
| record_format | Article |
| series | Трансплантология (Москва) |
| spelling | doaj-art-c0a87505d1cb4150b6cf81d73867202f2025-08-04T10:31:16ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092018-08-0101384310.23873/2074-0506-2009-0-1-38-43227Transjugular intrahepatic portocaval shunting as a preparation phase for liver transplantationP. G. Tarazov0D. A. Granov1A. A. Polikarpov2M. I. Generalov3I. O. Rutkin4O. A. Gerasimova5F. K. Zherebtsov6Russian Research Center of Radiology and Surgical TechnologiesRussian Research Center of Radiology and Surgical TechnologiesRussian Research Center of Radiology and Surgical TechnologiesRussian Research Center of Radiology and Surgical TechnologiesRussian Research Center of Radiology and Surgical TechnologiesRussian Research Center of Radiology and Surgical TechnologiesRussian Research Center of Radiology and Surgical TechnologiesObjective: to assess the first results of transjugular intrahepatic portocaval shunting (TIPS) as a technique for preventing portal hypertension complications in patients in the period of waiting for a donor liver.Subjects and methods. TIPS was performed in 6 patients on the list of waiting for orthotopic liver transplantation (OLT). The indications for TIPS were current (n=1) or high-risk recurrent hemorrhages from the esophageal varices and stomach (n=4) and diuretic-resistant ascitis (n=1).Results. TIPS was successfully carried out in all the patients. The portovenous gradient was reduced by 2—3 times (to 9—12 mm Hg). A further follow-up revealed recurrent varicose hemorrhage or ascitis in none patients. Doppler study indicated that the shunt showed a good function. OLT was successfully made in 3 patients 2, 8, and 19 months after TIPS; one female patient had been waiting for OLT for 5 months; 2 patients died from sepsis and hepatic failure following 1 and 5 months, respectively.Conclusion. The first results suggest that in patients with hepatic cirrhosis complicated with portal hypertension, TIPS can be regarded as a safety bridge while waiting for a donor liver.https://www.jtransplantologiya.ru/jour/article/view/238portocaval shuntintervention radiologyhepatic cirrhosisportal hypertensionorthotopic liver transplantation |
| spellingShingle | P. G. Tarazov D. A. Granov A. A. Polikarpov M. I. Generalov I. O. Rutkin O. A. Gerasimova F. K. Zherebtsov Transjugular intrahepatic portocaval shunting as a preparation phase for liver transplantation Трансплантология (Москва) portocaval shunt intervention radiology hepatic cirrhosis portal hypertension orthotopic liver transplantation |
| title | Transjugular intrahepatic portocaval shunting as a preparation phase for liver transplantation |
| title_full | Transjugular intrahepatic portocaval shunting as a preparation phase for liver transplantation |
| title_fullStr | Transjugular intrahepatic portocaval shunting as a preparation phase for liver transplantation |
| title_full_unstemmed | Transjugular intrahepatic portocaval shunting as a preparation phase for liver transplantation |
| title_short | Transjugular intrahepatic portocaval shunting as a preparation phase for liver transplantation |
| title_sort | transjugular intrahepatic portocaval shunting as a preparation phase for liver transplantation |
| topic | portocaval shunt intervention radiology hepatic cirrhosis portal hypertension orthotopic liver transplantation |
| url | https://www.jtransplantologiya.ru/jour/article/view/238 |
| work_keys_str_mv | AT pgtarazov transjugularintrahepaticportocavalshuntingasapreparationphaseforlivertransplantation AT dagranov transjugularintrahepaticportocavalshuntingasapreparationphaseforlivertransplantation AT aapolikarpov transjugularintrahepaticportocavalshuntingasapreparationphaseforlivertransplantation AT migeneralov transjugularintrahepaticportocavalshuntingasapreparationphaseforlivertransplantation AT iorutkin transjugularintrahepaticportocavalshuntingasapreparationphaseforlivertransplantation AT oagerasimova transjugularintrahepaticportocavalshuntingasapreparationphaseforlivertransplantation AT fkzherebtsov transjugularintrahepaticportocavalshuntingasapreparationphaseforlivertransplantation |