Deep cutaneous phaeohyphomycosis caused by Cladophialophora boppii: A case report
Cladophialophora boppii is a dematiaceous fungus rarely causing cutaneous and respiratory infections. We present a case of deep cutaneous infection in a 69-year-old patient in the Netherlands with stage IV breast cancer on dexamethasone therapy. The patient exhibited a skin plaque lesion, and biopsy...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-09-01
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| Series: | Medical Mycology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211753925000260 |
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| author | Thuy Thanh Cavens Janneke de Vries Suzanne Verleisdonk-Bolhaar Jochem B. Buil Arienne van Marion |
| author_facet | Thuy Thanh Cavens Janneke de Vries Suzanne Verleisdonk-Bolhaar Jochem B. Buil Arienne van Marion |
| author_sort | Thuy Thanh Cavens |
| collection | DOAJ |
| description | Cladophialophora boppii is a dematiaceous fungus rarely causing cutaneous and respiratory infections. We present a case of deep cutaneous infection in a 69-year-old patient in the Netherlands with stage IV breast cancer on dexamethasone therapy. The patient exhibited a skin plaque lesion, and biopsy revealed pigmented, septate hyphae without muriform cells, consistent with a diagnosis of phaeohyphomycosis. Surgical excision and culture confirmed C. boppii. Afterwards the patient received a three-week course of itraconazole, which led to infection resolution. This report and review of literature underscores the diagnostic and therapeutic approaches for managing deep cutaneous infections caused by C. boppii. |
| format | Article |
| id | doaj-art-c084fe6ac17748a0846b93a692ea4fd2 |
| institution | Matheson Library |
| issn | 2211-7539 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medical Mycology Case Reports |
| spelling | doaj-art-c084fe6ac17748a0846b93a692ea4fd22025-07-16T04:55:46ZengElsevierMedical Mycology Case Reports2211-75392025-09-0149100717Deep cutaneous phaeohyphomycosis caused by Cladophialophora boppii: A case reportThuy Thanh Cavens0Janneke de Vries1Suzanne Verleisdonk-Bolhaar2Jochem B. Buil3Arienne van Marion4Department of Pathology VieCuri, Tegelseweg 210, 5912 BL Venlo, NetherlandsDepartment of Medical Microbiology Viecuri, Tegelseweg 210, 5912 BL Venlo, NetherlandsDepartment of Dermatology Viecuri, Tegelseweg 210, 5912 BL Venlo, NetherlandsDepartment of Medical Microbiology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525 GA Nijmegen, Netherlands; Corresponding author.Department of Pathology VieCuri, Tegelseweg 210, 5912 BL Venlo, NetherlandsCladophialophora boppii is a dematiaceous fungus rarely causing cutaneous and respiratory infections. We present a case of deep cutaneous infection in a 69-year-old patient in the Netherlands with stage IV breast cancer on dexamethasone therapy. The patient exhibited a skin plaque lesion, and biopsy revealed pigmented, septate hyphae without muriform cells, consistent with a diagnosis of phaeohyphomycosis. Surgical excision and culture confirmed C. boppii. Afterwards the patient received a three-week course of itraconazole, which led to infection resolution. This report and review of literature underscores the diagnostic and therapeutic approaches for managing deep cutaneous infections caused by C. boppii.http://www.sciencedirect.com/science/article/pii/S2211753925000260PhaeohyphomycosisCladophialphora boppiiDeep cutaneous mycosisPlaque lesionDematiaceous fungi |
| spellingShingle | Thuy Thanh Cavens Janneke de Vries Suzanne Verleisdonk-Bolhaar Jochem B. Buil Arienne van Marion Deep cutaneous phaeohyphomycosis caused by Cladophialophora boppii: A case report Medical Mycology Case Reports Phaeohyphomycosis Cladophialphora boppii Deep cutaneous mycosis Plaque lesion Dematiaceous fungi |
| title | Deep cutaneous phaeohyphomycosis caused by Cladophialophora boppii: A case report |
| title_full | Deep cutaneous phaeohyphomycosis caused by Cladophialophora boppii: A case report |
| title_fullStr | Deep cutaneous phaeohyphomycosis caused by Cladophialophora boppii: A case report |
| title_full_unstemmed | Deep cutaneous phaeohyphomycosis caused by Cladophialophora boppii: A case report |
| title_short | Deep cutaneous phaeohyphomycosis caused by Cladophialophora boppii: A case report |
| title_sort | deep cutaneous phaeohyphomycosis caused by cladophialophora boppii a case report |
| topic | Phaeohyphomycosis Cladophialphora boppii Deep cutaneous mycosis Plaque lesion Dematiaceous fungi |
| url | http://www.sciencedirect.com/science/article/pii/S2211753925000260 |
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