Magnetic core-shell nanoparticles for Hyperthermia: A numerical study of soft and hard core-shell magnetic materials in liver tissue based on dual phase lag model
In this article, local hyperthermia using core-shell magnetic nanoparticles based on soft and hard magnetic ferrite phases, comprising Zn 0.4Co 0.6Fe 2O 4 @Zn 0.4 Mn 0.6 Fe 2O 4, under the influence of an AC magnetic field, has been numerically investigated to simulate heat distribution and tumor de...
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Elsevier
2025-09-01
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| Series: | Biochemistry and Biophysics Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405580825001712 |
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| author | M. Moshtagh M. Servatkhah S. Hosseini Gh Solookinejad |
| author_facet | M. Moshtagh M. Servatkhah S. Hosseini Gh Solookinejad |
| author_sort | M. Moshtagh |
| collection | DOAJ |
| description | In this article, local hyperthermia using core-shell magnetic nanoparticles based on soft and hard magnetic ferrite phases, comprising Zn 0.4Co 0.6Fe 2O 4 @Zn 0.4 Mn 0.6 Fe 2O 4, under the influence of an AC magnetic field, has been numerically investigated to simulate heat distribution and tumor destruction in liver tissue.It is observed that the dual-phase-lag (DPL) model predicts the maximum temperature lower than both the Pennes bioheat and the single-phase-lag (SPL) model. In addition simulation of temperature distribution over time considering different core-shell nanoparticles in AC magnetic field, has been performed using DPL model. The highest temperature is related to Zn 0.4 Co 0.6 Fe 2O4 @Zn 0.4 Mn 0.6 Fe 2O4 and the lowest temperature is related to MnFe2O4.We have concluded that these combinations maximize the properties of magnetic nanoparticles and have higher SLP values and more power dissipation of magnetic nanoparticles compared to magnetic nanoparticles of MnFe2O 4, MnFe2O4 @ CoFe2O4 and CoFe2O4 @MnFe2O4.Two-dimensional temperature distribution simulation over time in liver tissue has been performed using DPL model to quantitatively investigate the tumor temperature in different locations. The results show that temperature curves is a Gaussian-like distribution. The temperature curve is symmetric around the y axis. Temperature is maximum at the center of the tumor and decreases radially outward. |
| format | Article |
| id | doaj-art-c06efad9cdea4e3b8c7a46378053ba93 |
| institution | Matheson Library |
| issn | 2405-5808 |
| language | English |
| publishDate | 2025-09-01 |
| publisher | Elsevier |
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| series | Biochemistry and Biophysics Reports |
| spelling | doaj-art-c06efad9cdea4e3b8c7a46378053ba932025-06-29T04:52:28ZengElsevierBiochemistry and Biophysics Reports2405-58082025-09-0143102084Magnetic core-shell nanoparticles for Hyperthermia: A numerical study of soft and hard core-shell magnetic materials in liver tissue based on dual phase lag modelM. Moshtagh0M. Servatkhah1S. Hosseini2Gh Solookinejad3Department of Physics, Marvdasht Branch, Islamic Azad University, Marvdasht, IranDepartment of Physics, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran; Department of Physics, Nanotechnology Research Center, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran; Corresponding author. Department of Physics, Marvdasht Branch, Islamic Azad University, Marvdasht, IranDepartment of Physics, Nanotechnology Research Center, Marvdasht Branch, Islamic Azad University, Marvdasht, IranDepartment of Physics, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran; Department of Physics, Nanotechnology Research Center, Marvdasht Branch, Islamic Azad University, Marvdasht, IranIn this article, local hyperthermia using core-shell magnetic nanoparticles based on soft and hard magnetic ferrite phases, comprising Zn 0.4Co 0.6Fe 2O 4 @Zn 0.4 Mn 0.6 Fe 2O 4, under the influence of an AC magnetic field, has been numerically investigated to simulate heat distribution and tumor destruction in liver tissue.It is observed that the dual-phase-lag (DPL) model predicts the maximum temperature lower than both the Pennes bioheat and the single-phase-lag (SPL) model. In addition simulation of temperature distribution over time considering different core-shell nanoparticles in AC magnetic field, has been performed using DPL model. The highest temperature is related to Zn 0.4 Co 0.6 Fe 2O4 @Zn 0.4 Mn 0.6 Fe 2O4 and the lowest temperature is related to MnFe2O4.We have concluded that these combinations maximize the properties of magnetic nanoparticles and have higher SLP values and more power dissipation of magnetic nanoparticles compared to magnetic nanoparticles of MnFe2O 4, MnFe2O4 @ CoFe2O4 and CoFe2O4 @MnFe2O4.Two-dimensional temperature distribution simulation over time in liver tissue has been performed using DPL model to quantitatively investigate the tumor temperature in different locations. The results show that temperature curves is a Gaussian-like distribution. The temperature curve is symmetric around the y axis. Temperature is maximum at the center of the tumor and decreases radially outward.http://www.sciencedirect.com/science/article/pii/S2405580825001712Magnetic nanoparticlesHyperthermiaCore-shellDual-phase-lagLiver tissue |
| spellingShingle | M. Moshtagh M. Servatkhah S. Hosseini Gh Solookinejad Magnetic core-shell nanoparticles for Hyperthermia: A numerical study of soft and hard core-shell magnetic materials in liver tissue based on dual phase lag model Biochemistry and Biophysics Reports Magnetic nanoparticles Hyperthermia Core-shell Dual-phase-lag Liver tissue |
| title | Magnetic core-shell nanoparticles for Hyperthermia: A numerical study of soft and hard core-shell magnetic materials in liver tissue based on dual phase lag model |
| title_full | Magnetic core-shell nanoparticles for Hyperthermia: A numerical study of soft and hard core-shell magnetic materials in liver tissue based on dual phase lag model |
| title_fullStr | Magnetic core-shell nanoparticles for Hyperthermia: A numerical study of soft and hard core-shell magnetic materials in liver tissue based on dual phase lag model |
| title_full_unstemmed | Magnetic core-shell nanoparticles for Hyperthermia: A numerical study of soft and hard core-shell magnetic materials in liver tissue based on dual phase lag model |
| title_short | Magnetic core-shell nanoparticles for Hyperthermia: A numerical study of soft and hard core-shell magnetic materials in liver tissue based on dual phase lag model |
| title_sort | magnetic core shell nanoparticles for hyperthermia a numerical study of soft and hard core shell magnetic materials in liver tissue based on dual phase lag model |
| topic | Magnetic nanoparticles Hyperthermia Core-shell Dual-phase-lag Liver tissue |
| url | http://www.sciencedirect.com/science/article/pii/S2405580825001712 |
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