Ferroptosis and Metabolic Dysregulation: Emerging Chemical Targets in Cancer and Infection
The distinctive nature of ferroptosis is that it is induced chemically and signifies a regulated cell death dependent on iron-dependent lipid peroxidation. The mechanism of ferroptosis involves oxidative damage to the membrane lipids. It differs from apoptosis and necroptosis, triggering metabolic c...
Saved in:
Main Authors: | Marta Pawłowska, Jarosław Nuszkiewicz, Dorian Julian Jarek, Alina Woźniak |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2025-07-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/30/14/3020 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Targeting Ferroptosis in Tumors: Novel Marine-Derived Compounds as Regulators of Lipid Peroxidation and GPX4 Signaling
by: Yimao Wu, et al.
Published: (2025-06-01) -
Ferroptosis is important for Toxoplasma gondii replication and virulence in vitro and in vivo
by: Ling-Yu Li, et al.
Published: (2025-12-01) -
Exosomal miR-2137 from cadmium-treated hepatocytes drives renal ferroptosis via GPX4 suppression and is alleviated by selenium
by: Qian Wen, et al.
Published: (2025-07-01) -
Atp7a deficiency induces axonal and myelin developmental defects in zebrafish via ferroptosis
by: You Wu, et al.
Published: (2025-09-01) -
Taurine Attenuates Disuse Muscle Atrophy Through Modulation of the xCT-GSH-GPX4 and AMPK-ACC-ACSL4 Pathways
by: Xi Liu, et al.
Published: (2025-07-01)