ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES
Abstract. The review article concerns various features of PAX-5 (paired box 5) transcription factor, its structure, functions, regulation of activity, involvement into differentiation and activation of B lymphocytes, switching to IgE synthesis, its role in oncogenesis, and a putative r...
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| Format: | Article |
| Language: | Russian |
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St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2014-07-01
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| Series: | Медицинская иммунология |
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| Online Access: | https://www.mimmun.ru/mimmun/article/view/597 |
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| author | V. N. Mineev L. N. Sorokina M. A. Nyoma V. A. Ivanov G. I. Lipkin |
| author_facet | V. N. Mineev L. N. Sorokina M. A. Nyoma V. A. Ivanov G. I. Lipkin |
| author_sort | V. N. Mineev |
| collection | DOAJ |
| description | Abstract. The review article concerns various features of PAX-5 (paired box 5) transcription factor, its structure, functions, regulation of activity, involvement into differentiation and activation of B lymphocytes, switching to IgE synthesis, its role in oncogenesis, and a putative role of this factor for development of bronchial asthma.Further insight into specific properties of PAX-5 factor in bronchial asthma may provide a promising approach to studying mechanisms of this disorder. (Med. Immunol., 2011, vol. 13, N 6, pp 569-580) |
| format | Article |
| id | doaj-art-c03e99b7abf6428cb2dbdeda96bcdfe4 |
| institution | Matheson Library |
| issn | 1563-0625 2313-741X |
| language | Russian |
| publishDate | 2014-07-01 |
| publisher | St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists |
| record_format | Article |
| series | Медицинская иммунология |
| spelling | doaj-art-c03e99b7abf6428cb2dbdeda96bcdfe42025-08-04T14:30:32ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0113656958010.15789/1563-0625-2011-6-569-580594ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSESV. N. Mineev0L. N. Sorokina1M. A. Nyoma2V. A. Ivanov3G. I. Lipkin4Санкт-Петербургский государственный медицинский университет имени акад. И.П. Павлова, Санкт- ПетербургСанкт-Петербургский государственный медицинский университет имени акад. И.П. Павлова, Санкт- ПетербургСанкт-Петербургский государственный медицинский университет имени акад. И.П. Павлова, Санкт- ПетербургСанкт-Петербургский государственный медицинский университет имени акад. И.П. Павлова, Санкт- ПетербургСанкт-Петербургский государственный медицинский университет имени акад. И.П. Павлова, Санкт- ПетербургAbstract. The review article concerns various features of PAX-5 (paired box 5) transcription factor, its structure, functions, regulation of activity, involvement into differentiation and activation of B lymphocytes, switching to IgE synthesis, its role in oncogenesis, and a putative role of this factor for development of bronchial asthma.Further insight into specific properties of PAX-5 factor in bronchial asthma may provide a promising approach to studying mechanisms of this disorder. (Med. Immunol., 2011, vol. 13, N 6, pp 569-580)https://www.mimmun.ru/mimmun/article/view/597pax-5transcription factorsb lymphocytesbronchial asthmaige |
| spellingShingle | V. N. Mineev L. N. Sorokina M. A. Nyoma V. A. Ivanov G. I. Lipkin ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES Медицинская иммунология pax-5 transcription factors b lymphocytes bronchial asthma ige |
| title | ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES |
| title_full | ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES |
| title_fullStr | ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES |
| title_full_unstemmed | ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES |
| title_short | ROLE OF PAX-5 TRANSCRIPTION FACTOR IN IMMUNOLOGICAL PROCESSES |
| title_sort | role of pax 5 transcription factor in immunological processes |
| topic | pax-5 transcription factors b lymphocytes bronchial asthma ige |
| url | https://www.mimmun.ru/mimmun/article/view/597 |
| work_keys_str_mv | AT vnmineev roleofpax5transcriptionfactorinimmunologicalprocesses AT lnsorokina roleofpax5transcriptionfactorinimmunologicalprocesses AT manyoma roleofpax5transcriptionfactorinimmunologicalprocesses AT vaivanov roleofpax5transcriptionfactorinimmunologicalprocesses AT gilipkin roleofpax5transcriptionfactorinimmunologicalprocesses |