Applications in osteochondral organoids for osteoarthritis research: from pathomimetic modeling to tissue engineering repair

Osteoarthritis (OA) is a prevalent degenerative joint disorder characterized by complex tissue interactions, featuring cartilage degradation, synovitis, and aberrant subchondral bone remodeling. Current therapies often fail to halt disease progression and typically lack comprehensive strategies targ...

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Bibliographic Details
Main Authors: Yingguang Jiao, Shanyu Lu, Jianwei Zhang, Junping Zhen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1629608/full
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