Statins and diabetes mellitus: risks and benefits

Patients with diabetes mellitus (DM) are at a high risk of cardiovascular events (CVE). Currently, the predominant clinical strategy of the CVE prevention in DM patients is aggressive lowering of low-density lipoprotein cholesterol and blood pressure levels. In this clinical group, statins are among...

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Main Authors: O. M. Drapkina, O. N. Korneeva, A. F. Sheptulina
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2012-12-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/2038
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author O. M. Drapkina
O. N. Korneeva
A. F. Sheptulina
author_facet O. M. Drapkina
O. N. Korneeva
A. F. Sheptulina
author_sort O. M. Drapkina
collection DOAJ
description Patients with diabetes mellitus (DM) are at a high risk of cardiovascular events (CVE). Currently, the predominant clinical strategy of the CVE prevention in DM patients is aggressive lowering of low-density lipoprotein cholesterol and blood pressure levels. In this clinical group, statins are among the most widely used pharmacological agents. Recent clinical evidence suggests that statin therapy could be associated with an increased risk of DM. Both clinicians and researchers need to reevaluate the issue of statin safety in the patients at a higher CVE risk. This review focuses on the problem of DM development in statin-treated patients.
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publisher «SILICEA-POLIGRAF» LLC
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series Кардиоваскулярная терапия и профилактика
spelling doaj-art-bf21b96a7a2a4e8bb08c5a5d7f45b5cb2025-08-04T12:50:18Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252012-12-01116859010.15829/1728-8800-2012-6-85-901750Statins and diabetes mellitus: risks and benefitsO. M. Drapkina0O. N. Korneeva1A. F. Sheptulina2I. M. Sechenov First Moscow State Medical University, MoscowI. M. Sechenov First Moscow State Medical University, MoscowI. M. Sechenov First Moscow State Medical University, MoscowPatients with diabetes mellitus (DM) are at a high risk of cardiovascular events (CVE). Currently, the predominant clinical strategy of the CVE prevention in DM patients is aggressive lowering of low-density lipoprotein cholesterol and blood pressure levels. In this clinical group, statins are among the most widely used pharmacological agents. Recent clinical evidence suggests that statin therapy could be associated with an increased risk of DM. Both clinicians and researchers need to reevaluate the issue of statin safety in the patients at a higher CVE risk. This review focuses on the problem of DM development in statin-treated patients.https://cardiovascular.elpub.ru/jour/article/view/2038statinsdiabetes mellituscardiovascular diseasepancreatic β-cells
spellingShingle O. M. Drapkina
O. N. Korneeva
A. F. Sheptulina
Statins and diabetes mellitus: risks and benefits
Кардиоваскулярная терапия и профилактика
statins
diabetes mellitus
cardiovascular disease
pancreatic β-cells
title Statins and diabetes mellitus: risks and benefits
title_full Statins and diabetes mellitus: risks and benefits
title_fullStr Statins and diabetes mellitus: risks and benefits
title_full_unstemmed Statins and diabetes mellitus: risks and benefits
title_short Statins and diabetes mellitus: risks and benefits
title_sort statins and diabetes mellitus risks and benefits
topic statins
diabetes mellitus
cardiovascular disease
pancreatic β-cells
url https://cardiovascular.elpub.ru/jour/article/view/2038
work_keys_str_mv AT omdrapkina statinsanddiabetesmellitusrisksandbenefits
AT onkorneeva statinsanddiabetesmellitusrisksandbenefits
AT afsheptulina statinsanddiabetesmellitusrisksandbenefits