Targeting Biomarkers of Proliferation and Inflammation (Ki67, p53, and COX-2) in Actinic Keratoses with Photodynamic Therapy

Targeting Biomarkers of Proliferation and Inflammation (Ki67, p53, and COX-2) in Actinic Keratoses with Photodynamic Therapy

<b>Background</b>: Actinic keratoses (AKs) are common pre-neoplastic lesions that may progress to cutaneous squamous cell carcinoma (cSCC). Photodynamic therapy (PDT) is an effective field-directed treatment for AK, but its impact on key biomarkers remains unclear. This study evaluates t...

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Main Authors: Justyna Ceryn, Aleksandra Lesiak, Magdalena Ciążyńska, Dorota Sobolewska-Sztychny, Marcin Noweta, Olga Stasikowska-Kanicka, Karol Ciążyński, Iris Zalaudek, Joanna Narbutt
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
Subjects:
actinic keratosis
photodynamic therapy
Ki67
p53
COX-2
Online Access:https://www.mdpi.com/2227-9059/13/6/1487
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https://www.mdpi.com/2227-9059/13/6/1487

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