Pharmacokinetics of Olivamide after Bolus Administration in Rats and Rabbits (a Pilot Study)

Pharmacokinetics of Olivamide after Bolus Administration in Rats and Rabbits (a Pilot Study)

The pharmacokinetics of olivamide, a semisynthetic antitumor derivate of olivomycin A, were studied in rats and rabbits after bolus administration. Plasma concentrations of olivamide were determined by an HPLC assay. The decrease in olivamide levels in blood plasma was biphasic in both rats and rabb...

Full description

Saved in:
Bibliographic Details
Main Authors: Yu. A. Portnoy, S. A. Dovzhenko, M. B. Kobrin, M. I. Treshalin, V. A. Golobrodo, A. N. Tevyashova, A. A. Firsov
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2020-05-01
Series:Антибиотики и Химиотерапия
Subjects:
olivamide
pharmacokinetics
preclinical study
Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/35
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items