β-Glucan reprograms alveolar macrophages via neutrophil/IFNγ axis in a murine model of lung injury

β-Glucan reprograms alveolar macrophages via neutrophil/IFNγ axis in a murine model of lung injury

Alveolar macrophages (AMs) reside in the lower airways and play a crucial role in lung health and response to sterile inflammation and infections. AMs possess remarkable adaptability to different environmental challenges that can persist through their memory capacity (trained immunity). β-Glucan has...

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Bibliographic Details
Main Authors: Renaud Prevel, Erwan Pernet, Kim A Tran, Abderrahmane Sadek, Mina Sadeghi, Elizabeth Lapshina, Leonardo F Jurado, Arnold S Kristof, Mohieddine Moumni, Jeremie Poschmann, Maziar Divangahi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-07-01
Series:eLife
Subjects:
trained immunity
acute lung injury
β-glucan
Online Access:https://elifesciences.org/articles/102068
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