Immunoglobulins G from Patients with Systemic Sclerosis Modify the Molecular Signatures of Endothelial Cells

Immunoglobulins G from Patients with Systemic Sclerosis Modify the Molecular Signatures of Endothelial Cells

Objective Antinuclear antibodies (ANA) are powerful biomarkers in systemic sclerosis (SSc). Functional antibodies (FA) might be implicated in vasculopathy, in which endothelial cells (EC) are key players. We aimed to explore the effect of purified IgG from patients with SSc on omics signatures of EC...

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Main Authors: Eric Hachulla, David Launay, Alain Lescoat, Valérie Lecureur, Vincent Sobanski, Sylvain Dubucquoi, Martin Figeac, Aurélien Chepy, Solange Vivier, Fabrice Bray, Clément Chauvet, Abderrahmane Elhannani, Lucile Guilbert, Frédéric Leprêtre, Louisa Bourel, Christian Rolando
Format: Article
Language:English
Published: BMJ Publishing Group 2025-03-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/11/1/e004290.full
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https://rmdopen.bmj.com/content/11/1/e004290.full

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