THE PROGNOSTIC MODEL OF ANTITUMOR EFFECT OF TARGETED DRUGS IN IMMUNOTHERAPY
A prognostic model for constructing hypotheses about the relationship of combinations of cytokines with the proliferative activity of cancer cells is proposed. The model is based on the use of inductive inference methods. The methodology takes into account the synergistic interaction of cytokines an...
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| Những tác giả chính: | , , , , , |
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| Định dạng: | Bài viết |
| Ngôn ngữ: | Tiếng Nga |
| Được phát hành: |
MIREA - Russian Technological University
2016-08-01
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| Loạt: | Тонкие химические технологии |
| Những chủ đề: | |
| Truy cập trực tuyến: | https://www.finechem-mirea.ru/jour/article/view/42 |
| Các nhãn: |
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| Tóm tắt: | A prognostic model for constructing hypotheses about the relationship of combinations of cytokines with the proliferative activity of cancer cells is proposed. The model is based on the use of inductive inference methods. The methodology takes into account the synergistic interaction of cytokines and uses sequential construction of logical formulas for selecting groups of cytokines, a statistical analysis of contingency tables and logical integration of the obtained estimates. Implementation of the proposed method in the information system of forecasting the effect of targeted anticancer drugs in immunotherapy will greatly accelerate research in this area. |
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| số ISSN: | 2410-6593 2686-7575 |