Agmatine Mitigates Acetaminophen-induced Acute Liver Injury in Mice: Involvement of HMGB1/RAGE/NFκB and Nrf2/HO-1 Signaling Pathways

An overdose of acetaminophen (APAP) is considered one of the primary sources of drug-induced liver injury. This study aimed to explore the mechanism of agmatine (Agma) against APAP-induced acute liver injury (ALI) in mice. Mice were allocated into six groups: normal and Agma control, APAP, N-acetyl-...

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Bibliographic Details
Main Authors: Ahmed Abdelhady, Mohammed Ayman, Marwa Abdelmageed
Format: Article
Language:English
Published: Egyptian Society for Animal Management 2025-07-01
Series:Journal of Applied Veterinary Sciences
Subjects:
Online Access:https://javs.journals.ekb.eg/article_430380_3b67aab5efe00c114a388fde563eea06.pdf
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