Hybrids of Methylxanthines and Azoderivatives as Acetylcholinesterase Inhibitors: Structure–Activity Relationship Analysis
In this work, we synthesized methylxanthine and azobenzene derivatives, linked to secondary amines via a seven-carbon chain, to evaluate their acetylcholinesterase (AChE) inhibitory activity. Among the azobenzene compounds, <b>3a</b> exhibited the highest activity with an IC<sub>50...
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Main Authors: | Brunella Biscussi, Santiago Gundin, Martina Donozo, Ana Paula Murray |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-11-01
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Series: | Chemistry Proceedings |
Subjects: | |
Online Access: | https://www.mdpi.com/2673-4583/16/1/111 |
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