Mechanistic Models Predict Efficacy of CCR5‐Deficient Stem Cell Transplants in HIV Patient Populations

Combination antiretroviral therapy (cART) effectively suppresses viral load in HIV‐infected individuals, but it is not a cure. Bone marrow transplants using HIV‐resistant stem cells have renewed hope that cure is achievable but key questions remain e.g., what percentage of stem cells must be HIV‐res...

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Bibliographic Details
Main Authors: I Hosseini, F Mac Gabhann
Format: Article
Language:English
Published: Wiley 2016-02-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12059
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