Oxidative stress and endometriosis: review of the literature
Reactive oxygen forms (ROF) play an important role in modulating many physiological functions of the reproductive system, including the formation of endometriosis, are involved in the pathogenesis of infertility; There is a fine balance between ROF and antioxidants in the female reproductive process...
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| Format: | Article |
| Language: | Russian |
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Open Systems Publication
2021-06-01
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| Series: | Лечащий Врач |
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| Online Access: | https://journal.lvrach.ru/jour/article/view/246 |
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| author | L. V. Adamyan M. M. Sonova K. N. Arslanyan O. N. Loginova E. I. Kharchenko |
| author_facet | L. V. Adamyan M. M. Sonova K. N. Arslanyan O. N. Loginova E. I. Kharchenko |
| author_sort | L. V. Adamyan |
| collection | DOAJ |
| description | Reactive oxygen forms (ROF) play an important role in modulating many physiological functions of the reproductive system, including the formation of endometriosis, are involved in the pathogenesis of infertility; There is a fine balance between ROF and antioxidants in the female reproductive process, which supports redox homeostasis. Oxidative stress occurs under conditions where the balance between ROF production and antioxidant protection is disturbed, and this may be due either to insufficient antioxidant protection or to excessive ROF production. Various data confirm the role of oxidative stress in the development and progression of endometriosis. This observation may open the way to assessment of therapeutic approaches aimed at correcting oxidative imbalance: the status of oxidative stress may be the key to treatment and, ultimately, to the prevention of endometriosis. In particular, in the future, clinical trials will help to better clarify the effectiveness of antioxidants as a potential therapy for endometriosis. |
| format | Article |
| id | doaj-art-bc6396a7d2ad4849b59d25cf34e1c6fd |
| institution | Matheson Library |
| issn | 1560-5175 2687-1181 |
| language | Russian |
| publishDate | 2021-06-01 |
| publisher | Open Systems Publication |
| record_format | Article |
| series | Лечащий Врач |
| spelling | doaj-art-bc6396a7d2ad4849b59d25cf34e1c6fd2025-08-03T13:02:48ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812021-06-010122025245Oxidative stress and endometriosis: review of the literatureL. V. Adamyan0M. M. Sonova1K. N. Arslanyan2O. N. Loginova3E. I. KharchenkoФГБОУ ВО МГМСУ им. А. И. Евдокимова МЗ РФФГБОУ ВО МГМСУ им. А. И. Евдокимова МЗ РФФГБОУ ВО МГМСУ им. А. И. Евдокимова МЗ РФФГБОУ ВО МГМСУ им. А. И. Евдокимова МЗ РФReactive oxygen forms (ROF) play an important role in modulating many physiological functions of the reproductive system, including the formation of endometriosis, are involved in the pathogenesis of infertility; There is a fine balance between ROF and antioxidants in the female reproductive process, which supports redox homeostasis. Oxidative stress occurs under conditions where the balance between ROF production and antioxidant protection is disturbed, and this may be due either to insufficient antioxidant protection or to excessive ROF production. Various data confirm the role of oxidative stress in the development and progression of endometriosis. This observation may open the way to assessment of therapeutic approaches aimed at correcting oxidative imbalance: the status of oxidative stress may be the key to treatment and, ultimately, to the prevention of endometriosis. In particular, in the future, clinical trials will help to better clarify the effectiveness of antioxidants as a potential therapy for endometriosis.https://journal.lvrach.ru/jour/article/view/246oxidative stressendometriosisinfertilitygenesfollicular fluidperitoneum |
| spellingShingle | L. V. Adamyan M. M. Sonova K. N. Arslanyan O. N. Loginova E. I. Kharchenko Oxidative stress and endometriosis: review of the literature Лечащий Врач oxidative stress endometriosis infertility genes follicular fluid peritoneum |
| title | Oxidative stress and endometriosis: review of the literature |
| title_full | Oxidative stress and endometriosis: review of the literature |
| title_fullStr | Oxidative stress and endometriosis: review of the literature |
| title_full_unstemmed | Oxidative stress and endometriosis: review of the literature |
| title_short | Oxidative stress and endometriosis: review of the literature |
| title_sort | oxidative stress and endometriosis review of the literature |
| topic | oxidative stress endometriosis infertility genes follicular fluid peritoneum |
| url | https://journal.lvrach.ru/jour/article/view/246 |
| work_keys_str_mv | AT lvadamyan oxidativestressandendometriosisreviewoftheliterature AT mmsonova oxidativestressandendometriosisreviewoftheliterature AT knarslanyan oxidativestressandendometriosisreviewoftheliterature AT onloginova oxidativestressandendometriosisreviewoftheliterature AT eikharchenko oxidativestressandendometriosisreviewoftheliterature |