SUCCESSFUL USE OF ETANERCEPT IN A PATIENT WITH POLYARTICULAR JUVENILE IDIOPATHIC ARTHRITIS WITH AN OVERVIEW OF THE PREDICTORS OF A GOOD RESPONSE TO ONGOING THERAPY
The article presents a case of polyarticular juvenile idiopathic arthritis resistant to methotrexate therapy and nonsteroidal antiinflammatory drugs. The child was prescribed a tumor necrosis factor inhibitor etanercept at a dose of 0.4 mg/kg body weight2 times/week. The treatm...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
"Paediatrician" Publishers LLC
2017-09-01
|
| Series: | Вопросы современной педиатрии |
| Subjects: | |
| Online Access: | https://vsp.spr-journal.ru/jour/article/view/1791 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | The article presents a case of polyarticular juvenile idiopathic arthritis resistant to methotrexate therapy and nonsteroidal antiinflammatory drugs. The child was prescribed a tumor necrosis factor inhibitor etanercept at a dose of 0.4 mg/kg body weight2 times/week. The treatment with etanercept induced remission of the disease, ensured the function restoration in the joints. The predictors of a good response to etanercept were the younger age, the short course of the disease, the use of a small number of immunosuppressants before prescription of etanercept, the absence of concomitant use of glucocorticosteroids, and the absence of uveitis. |
|---|---|
| ISSN: | 1682-5527 1682-5535 |