Eimeria tenella aspartyl protease is identified as a potential TLR15 ligand and activates macrophages and dendritic cells in chickens

Eimeria tenella aspartyl protease is identified as a potential TLR15 ligand and activates macrophages and dendritic cells in chickens

Toll-like receptor (TLR)-mediated recognition of specific ligands is critical for initiating innate immunity against Eimeria infections. However, the avian-specific TLR15 has unclear immunological functions, including its specific ligands and role in anti-coccidia immunity. In this study, an asparty...

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Bibliographic Details
Main Authors: Chen Chen, Zhichao Men, Xianglin Pu, Mingmin Lu, Lixin Xu, Ruofeng Yan, Xiangrui Li, Xiaokai Song
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Poultry Science
Subjects:
Innate immunity
Toll-like receptor 15
Aspartyl proteases
Bone marrow-derived dendritic cells
Eimeria tenella
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579125007680
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