Current status of pharmacotherapy for primary sclerosing cholangitis

Current status of pharmacotherapy for primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) represents a cholestatic disease hallmarked by persistent and progressive inflammation of the bile ducts. Despite its low incidence and unfavorable prognosis, there is no pharmacological therapy capable of altering the course of PSC, and liver transplantation is...

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Bibliographic Details
Main Authors: Hang Yang, Juan Zhen, Xiaoyan Huang, Minqi Chen, Hongsi Cui, Xia Sheng, Xinyu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Medicine
Subjects:
primary sclerosing cholangitis
ursodeoxycholic acid
Nor-UDCA
clinical trial
drug therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1544601/full
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