Neural Implants Without Active Implanted Electronics: Possibilities and Limitations of Transcutaneous Coupling in Miniaturized Active Implants
<italic>Goal:</italic> Transcutaneous coupling scheme for wireless powering and signal in active implants are known for more than a decade. This study aimed to investigate the in vivo behavior of this approach to drive multiple channels of an implanted peripheral nerve interfaces. <it...
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IEEE
2025-01-01
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| Series: | IEEE Open Journal of Engineering in Medicine and Biology |
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| author | Patrick Kiele Gregor Laengle Martin Schmoll Cristian Pasluosta Ronny Pfeifer Martin Schuettler Oskar Aszmann Thomas Stieglitz |
| author_facet | Patrick Kiele Gregor Laengle Martin Schmoll Cristian Pasluosta Ronny Pfeifer Martin Schuettler Oskar Aszmann Thomas Stieglitz |
| author_sort | Patrick Kiele |
| collection | DOAJ |
| description | <italic>Goal:</italic> Transcutaneous coupling scheme for wireless powering and signal in active implants are known for more than a decade. This study aimed to investigate the in vivo behavior of this approach to drive multiple channels of an implanted peripheral nerve interfaces. <italic>Methods:</italic> The stimulation signals were transmitted through the skin over two contacts to an intracorporeal counterpart which was connected to a cuff electrode with two channels. EMG after stimulation was measured to establish recruitment curves. <italic>Results:</italic> Limitations of transcutaneous coupling were found in the feasible complexity of the system. High electrical crosstalk in a multi-channel system reduces this approach to low channel applications, such as pain treatment. No significant influence of the pulse width or extracorporeal stimulation amplitude on the electrical crosstalk was observed. <italic>Conclusions:</italic> The study's findings provide insight into the behavior of the transcutaneous coupling scheme in vivo and highlight the limitations and areas of application. Our results indicate that transcutaneous coupling schemes are a promising alternative approach for wireless powering of implants, as it does not require complex implanted electronics, expensive sophisticated electronics, and hermetic enclosures. Physical constraints, however, limit the use in highly selective nerve stimulation scenarios. |
| format | Article |
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| language | English |
| publishDate | 2025-01-01 |
| publisher | IEEE |
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| series | IEEE Open Journal of Engineering in Medicine and Biology |
| spelling | doaj-art-bbeec1292d4a45b5a0f7cc3ca13a451f2025-07-02T00:15:05ZengIEEEIEEE Open Journal of Engineering in Medicine and Biology2644-12762025-01-016697410.1109/OJEMB.2024.347726710710177Neural Implants Without Active Implanted Electronics: Possibilities and Limitations of Transcutaneous Coupling in Miniaturized Active ImplantsPatrick Kiele0https://orcid.org/0000-0002-0084-6634Gregor Laengle1https://orcid.org/0000-0003-1011-3482Martin Schmoll2https://orcid.org/0000-0001-6354-3879Cristian Pasluosta3https://orcid.org/0000-0001-5335-9840Ronny Pfeifer4https://orcid.org/0009-0009-2427-5002Martin Schuettler5https://orcid.org/0009-0005-1737-6922Oskar Aszmann6https://orcid.org/0000-0001-5530-726XThomas Stieglitz7https://orcid.org/0000-0002-7349-4254Laboratory of Biomedical Microtechnology at IMTEK and the BrainLinks-BrainTools Center, University of Freiburg, Freiburg, GermanyCenter of Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, AustriaLaboratory for Bionic Extremity Reconstruction and Rehabilitation Department of Plastic and Reconstructive Surgery, Medical University of Vienna, Vienna, AustriaLaboratory of Biomedical Microtechnology at IMTEK and the BrainLinks-BrainTools Center, University of Freiburg, Freiburg, GermanyCorTec GmbH, Freiburg, GermanyCorTec GmbH, Freiburg, GermanyLaboratory for Bionic Extremity Reconstruction and Rehabilitation Department of Plastic and Reconstructive Surgery, Medical University of Vienna, Vienna, AustriaLaboratory of Biomedical Microtechnology at IMTEK and the BrainLinks-BrainTools Center, University of Freiburg, Freiburg, Germany<italic>Goal:</italic> Transcutaneous coupling scheme for wireless powering and signal in active implants are known for more than a decade. This study aimed to investigate the in vivo behavior of this approach to drive multiple channels of an implanted peripheral nerve interfaces. <italic>Methods:</italic> The stimulation signals were transmitted through the skin over two contacts to an intracorporeal counterpart which was connected to a cuff electrode with two channels. EMG after stimulation was measured to establish recruitment curves. <italic>Results:</italic> Limitations of transcutaneous coupling were found in the feasible complexity of the system. High electrical crosstalk in a multi-channel system reduces this approach to low channel applications, such as pain treatment. No significant influence of the pulse width or extracorporeal stimulation amplitude on the electrical crosstalk was observed. <italic>Conclusions:</italic> The study's findings provide insight into the behavior of the transcutaneous coupling scheme in vivo and highlight the limitations and areas of application. Our results indicate that transcutaneous coupling schemes are a promising alternative approach for wireless powering of implants, as it does not require complex implanted electronics, expensive sophisticated electronics, and hermetic enclosures. Physical constraints, however, limit the use in highly selective nerve stimulation scenarios.https://ieeexplore.ieee.org/document/10710177/Electrodeneural implantskintelemetrytranscoutaneous coupling |
| spellingShingle | Patrick Kiele Gregor Laengle Martin Schmoll Cristian Pasluosta Ronny Pfeifer Martin Schuettler Oskar Aszmann Thomas Stieglitz Neural Implants Without Active Implanted Electronics: Possibilities and Limitations of Transcutaneous Coupling in Miniaturized Active Implants IEEE Open Journal of Engineering in Medicine and Biology Electrode neural implant skin telemetry transcoutaneous coupling |
| title | Neural Implants Without Active Implanted Electronics: Possibilities and Limitations of Transcutaneous Coupling in Miniaturized Active Implants |
| title_full | Neural Implants Without Active Implanted Electronics: Possibilities and Limitations of Transcutaneous Coupling in Miniaturized Active Implants |
| title_fullStr | Neural Implants Without Active Implanted Electronics: Possibilities and Limitations of Transcutaneous Coupling in Miniaturized Active Implants |
| title_full_unstemmed | Neural Implants Without Active Implanted Electronics: Possibilities and Limitations of Transcutaneous Coupling in Miniaturized Active Implants |
| title_short | Neural Implants Without Active Implanted Electronics: Possibilities and Limitations of Transcutaneous Coupling in Miniaturized Active Implants |
| title_sort | neural implants without active implanted electronics possibilities and limitations of transcutaneous coupling in miniaturized active implants |
| topic | Electrode neural implant skin telemetry transcoutaneous coupling |
| url | https://ieeexplore.ieee.org/document/10710177/ |
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