Remote outcomes in patients with cardiovascular diseases in outpatient practice: data from a 10-year follow-up within the RECVAZA registry
Aim. To evaluate outcomes over 10-year follow-up and risks of adverse events in patients with cardiovascular disease (CVD) within the outpatient registry.Material and methods. In the RECVAZA outpatient registry based on 3 Ryazan clinics, 3690 patients with CVD (age, 66,1±12,9 years; men, 28,0%) were...
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«SILICEA-POLIGRAF» LLC
2025-02-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/4269 |
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| author | M. M. Luk'yanov S. Yu. Martsevich S. S. Yakushin E. Yu. Andreenko K. G. Pereverzeva A. N. Kozminsky E. A. Pravkina V. G. Klyashtorny O. M. Drapkina |
| author_facet | M. M. Luk'yanov S. Yu. Martsevich S. S. Yakushin E. Yu. Andreenko K. G. Pereverzeva A. N. Kozminsky E. A. Pravkina V. G. Klyashtorny O. M. Drapkina |
| author_sort | M. M. Luk'yanov |
| collection | DOAJ |
| description | Aim. To evaluate outcomes over 10-year follow-up and risks of adverse events in patients with cardiovascular disease (CVD) within the outpatient registry.Material and methods. In the RECVAZA outpatient registry based on 3 Ryazan clinics, 3690 patients with CVD (age, 66,1±12,9 years; men, 28,0%) were observed. For 2012-2023 (follow-up, 8,2±3,3 years), the following outcomes were assessed: death, myocardial infarction (MI), stroke, hospitalization for CVD. Information on outcomes was obtained from medical records, surveys, electronic databases.Results. Over 10 years, 1595 patients (43,2%) died, 51% of whom died from CVD and 12% from cancer. The highest proportion of deaths was among patients with prior stroke (69,7%) and MI (61,5%) before inclusion in the registry, a combination of hypertension (HTN), coronary artery disease (CAD), heart failure (HF), atrial fibrillation (AF) — 79%, age ≥80 years — 85,9%. The highest all-cause and cardiovascular death risk was associated with age (hazard ratio (HR))=1,06 and HR=1,07; p<0,001); male sex (HR=1,70 and HR=1,62; p<0,001); prior stroke (HR=1,86 and HR=2,13; p<0,001); type 2 diabetes (HR=1,55 and HR=1,67; p<0,001); low hemoglobin level (HR=1,66 and HR=1,72; p<0,001); smoking (HR=1,51; p=0,001 and HR=1,72; p=0,003), respectively. The risk of MI was associated to the greatest extent with male sex and prior MI (HR=1,77 and HR=2,61; p<0,001), while the risk of stroke — with AF and prior stroke (HR=1,65 and 3,78; p<0,001) and systolic blood pressure <110 mm Hg (HR=2,72; p=0,01). Hospitalization for CVD no more than once per 2 years was associated with a lower risk of death (1,9 times), a higher frequency — with a higher risk (1,6 times).Conclusion. Over 10-year follow-up, 43,2% of patients with CVD died. The highest death rate was in patients with a history of stroke and MI, diabetes, with a combination of HTN, CAD, HF and AF, low hemoglobin levels. Hospitalization for CVD no more than once per 2 years was prognostically favorable, but with a higher frequency it was associated with an increased risk of death. |
| format | Article |
| id | doaj-art-bb6c81d1b1b6436aa4d66bdad6914d05 |
| institution | Matheson Library |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2025-02-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
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| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-bb6c81d1b1b6436aa4d66bdad6914d052025-08-04T12:50:33Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252025-02-01231210.15829/1728-8800-2024-42693142Remote outcomes in patients with cardiovascular diseases in outpatient practice: data from a 10-year follow-up within the RECVAZA registryM. M. Luk'yanov0S. Yu. Martsevich1S. S. Yakushin2E. Yu. Andreenko3K. G. Pereverzeva4A. N. Kozminsky5E. A. Pravkina6V. G. Klyashtorny7O. M. Drapkina8National Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicinePavlov Ryazan State Medical UniversityNational Medical Research Center for Therapy and Preventive MedicinePavlov Ryazan State Medical UniversityPavlov Ryazan State Medical UniversityPavlov Ryazan State Medical UniversityNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineAim. To evaluate outcomes over 10-year follow-up and risks of adverse events in patients with cardiovascular disease (CVD) within the outpatient registry.Material and methods. In the RECVAZA outpatient registry based on 3 Ryazan clinics, 3690 patients with CVD (age, 66,1±12,9 years; men, 28,0%) were observed. For 2012-2023 (follow-up, 8,2±3,3 years), the following outcomes were assessed: death, myocardial infarction (MI), stroke, hospitalization for CVD. Information on outcomes was obtained from medical records, surveys, electronic databases.Results. Over 10 years, 1595 patients (43,2%) died, 51% of whom died from CVD and 12% from cancer. The highest proportion of deaths was among patients with prior stroke (69,7%) and MI (61,5%) before inclusion in the registry, a combination of hypertension (HTN), coronary artery disease (CAD), heart failure (HF), atrial fibrillation (AF) — 79%, age ≥80 years — 85,9%. The highest all-cause and cardiovascular death risk was associated with age (hazard ratio (HR))=1,06 and HR=1,07; p<0,001); male sex (HR=1,70 and HR=1,62; p<0,001); prior stroke (HR=1,86 and HR=2,13; p<0,001); type 2 diabetes (HR=1,55 and HR=1,67; p<0,001); low hemoglobin level (HR=1,66 and HR=1,72; p<0,001); smoking (HR=1,51; p=0,001 and HR=1,72; p=0,003), respectively. The risk of MI was associated to the greatest extent with male sex and prior MI (HR=1,77 and HR=2,61; p<0,001), while the risk of stroke — with AF and prior stroke (HR=1,65 and 3,78; p<0,001) and systolic blood pressure <110 mm Hg (HR=2,72; p=0,01). Hospitalization for CVD no more than once per 2 years was associated with a lower risk of death (1,9 times), a higher frequency — with a higher risk (1,6 times).Conclusion. Over 10-year follow-up, 43,2% of patients with CVD died. The highest death rate was in patients with a history of stroke and MI, diabetes, with a combination of HTN, CAD, HF and AF, low hemoglobin levels. Hospitalization for CVD no more than once per 2 years was prognostically favorable, but with a higher frequency it was associated with an increased risk of death.https://cardiovascular.elpub.ru/jour/article/view/4269cardiovascular diseasesprospective registrymultimorbidityoutcomesdeath risk assessment |
| spellingShingle | M. M. Luk'yanov S. Yu. Martsevich S. S. Yakushin E. Yu. Andreenko K. G. Pereverzeva A. N. Kozminsky E. A. Pravkina V. G. Klyashtorny O. M. Drapkina Remote outcomes in patients with cardiovascular diseases in outpatient practice: data from a 10-year follow-up within the RECVAZA registry Кардиоваскулярная терапия и профилактика cardiovascular diseases prospective registry multimorbidity outcomes death risk assessment |
| title | Remote outcomes in patients with cardiovascular diseases in outpatient practice: data from a 10-year follow-up within the RECVAZA registry |
| title_full | Remote outcomes in patients with cardiovascular diseases in outpatient practice: data from a 10-year follow-up within the RECVAZA registry |
| title_fullStr | Remote outcomes in patients with cardiovascular diseases in outpatient practice: data from a 10-year follow-up within the RECVAZA registry |
| title_full_unstemmed | Remote outcomes in patients with cardiovascular diseases in outpatient practice: data from a 10-year follow-up within the RECVAZA registry |
| title_short | Remote outcomes in patients with cardiovascular diseases in outpatient practice: data from a 10-year follow-up within the RECVAZA registry |
| title_sort | remote outcomes in patients with cardiovascular diseases in outpatient practice data from a 10 year follow up within the recvaza registry |
| topic | cardiovascular diseases prospective registry multimorbidity outcomes death risk assessment |
| url | https://cardiovascular.elpub.ru/jour/article/view/4269 |
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