Development of a new N-terminomic method to study the pathodegradome of the Staphylococcus aureus V8 protease in human neutrophils

ABSTRACT Staphylococcus aureus is a notorious human pathogen that relies on an array of virulence factors to engender infection and evade the host-immune system. Among these are the secreted proteases, which promote pathogenesis by degrading host proteins and modulating host defenses. Human neutroph...

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Bibliographic Details
Main Authors: Emilee M. Mustor, Andrew M. Frey, Mary-Elizabeth Jobson, Dale Chaput, Lindsey Neil Shaw
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:mSystems
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Online Access:https://journals.asm.org/doi/10.1128/msystems.00697-25
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