A stable systemic infection of methicillin-resistant Staphylococcus aureus (MRSA) in cynomolgus macaques produces extended window for therapeutic intervention

A stable systemic infection of methicillin-resistant Staphylococcus aureus (MRSA) in cynomolgus macaques produces extended window for therapeutic intervention

IntroductionStaphylococcus aureus is a common gram-positive commensal that, upon entering the bloodstream, can cause devastating illness and death within hours or days. Methicillin-resistant S. aureus (MRSA) infections, now a leading cause of bloodstream infections worldwide, pose significant challe...

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Main Authors: Adrienne J. Gamblin, Max C. Peterson, Samantha S. Simon, Tatyana Orekov, Erica Penn, Gabriella Shumyatsky, Grishma Patel, Amanda Womer, Helal Kabir, Darnell Bushby, Jeanne Muench, Karen Feliciano, Fabian Paz, Brad Finneyfrock, Anthony Cook, Swagata Kar
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Microbiology
Subjects:
Staphylococcus aureus
MRSA
cynomolgus macaque
nonhuman primate
S. aureus bacteremia
bacterial infection model
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1601381/full
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https://www.frontiersin.org/articles/10.3389/fmicb.2025.1601381/full

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