Ten‐Eleven Translocation Family Proteins: Structure, Biological Functions, Diseases, and Targeted Therapy

QR Code

Ten‐Eleven Translocation Family Proteins: Structure, Biological Functions, Diseases, and Targeted Therapy

ABSTRACT Ten‐eleven translocation (TET) family proteins are Fe(II)‐ and α‐ketoglutarate‐dependent dioxygenases, comprising three family members: TET1, TET2, and TET3. These enzymes drive DNA demethylation by sequentially oxidizing 5‐methylcytosine to 5‐hydroxymethylcytosine, 5‐formylcytosine, and 5‐...

Full description

Saved in:

Bibliographic Details
Main Authors:	Junzhi Liang, Xinni Na, Lingbo Meng, Lixia He, Ting Shu, Yuanyuan Fang, Bowen Zhang, Zhongyu Zhao, Cuishan Guo, Tingting Li, Zhijing Na, Da Li, Xue Xiao
Format:	Article
Language:	English
Published:	Wiley 2025-07-01
Series:	MedComm
Subjects:	Biological functions Demethylation Diseases Ten‐eleven translocation Therapeutic strategies
Online Access:	https://doi.org/10.1002/mco2.70245
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Preface – Plus-minus ten years
by: T. Czigany
Published: (2017-01-01)

A fundação da Confraria das Onze Mil Virgens na colônia. // The foundation of the Confraternity of the Eleven Thousand Virgins in the colony.
by: Stela Beatriz Duarte
Published: (2012-06-01)

ALKBH5 in development: decoding the multifaceted roles of m6A demethylation in biological processes
by: Xinye Zhang, et al.
Published: (2025-08-01)

TET1: The epigenetic architect of clinical disease progression
by: Keyvan Jabbari, et al.
Published: (2025-09-01)

Differential expression of ten-eleven translocation genes in endometrial cancers
by: Piotr Ciesielski, et al.
Published: (2017-03-01)

Nirvāṇa and the ten Dharmas in the Altun Yaruk Sudur text
by: Kübra, et al.
Published: (2025-06-01)

BIOLOGICAL ACTIVITY OF STEROIDAL GLYCOSIDES FROM BULBS OF ALLIUM CYRILLII TEN. (ALLIACEAE)
by: N. V. Tolkachova, et al.
Published: (2015-09-01)

Ten tips to harnessing generative AI for high-quality MCQS in medical education assessment
by: Mohi Eldin Magzoub, et al.
Published: (2025-12-01)

Bacterial translocation in deceased organ donors
by: O. V. Petkevich, et al.
Published: (2025-01-01)

Asthenozoospermia in a patient with reciprocal translocation t(12;15): A case report
by: Tea Mladenić, et al.
Published: (2025-07-01)

Frequency‐Dependent Demethylation of Cancer DNAs by High‐Power Terahertz Radiation
by: Chaeyoon Kim, et al.
Published: (2025-07-01)

Preventing opioid prescribing for low back pain using multimodal mechanical stimulation vs. TENS: a randomized-controlled trial
by: Amy L. Baxter, et al.
Published: (2025-07-01)

Impairment of gut defense barrier and microbial translocation in HIV-infection
by: G. R. Khasanova
Published: (2014-09-01)

Legal Analysis of the Implementation of the Ten Steps to Successful Breastfeeding in Government Regulation Number 28 of 2024 to Support the Exclusive Breastfeeding Program in Indonesia
by: Ni Made Garnis Dolesgit
Published: (2025-07-01)

Global patterns and determinants of erosion-induced soil carbon translocation
by: Fangli Wei, et al.
Published: (2025-10-01)

Development and characterization of a novel common wheat–Mexico Rye T1DL·1RS translocation line with stripe rust and powdery mildew resistance
by: Jiao-jiao LI, et al.
Published: (2023-05-01)

Differential Diagnostics of Toxic Epidermal Necrolysis (Lyell’s Syndrome) in ICU: Case Reports
by: Yu. V. Molochkova, et al.
Published: (2022-01-01)

Nanopore sequencing and hybrid assembly: unraveling the genomic landscape of dollar spot with enhanced annotation and drug resistance profiling
by: Xiaojing Shi, et al.
Published: (2025-07-01)

Recruitment of Captive‐Reared Florida Grasshopper Sparrows After Translocation: Age of Release Matters
by: Juan C. Oteyza, et al.
Published: (2025-07-01)

Two management cases of intrauterine device translocation to the bladder
by: A. N. Nechiporenko
Published: (2024-07-01)

EVALUATION OF THE EFFECTIVENESS TRANSLOCATIONAL PROCTOPLASTY IN CHRONIC PARAPROCTITIS
by: N. V. Makarov
Published: (2015-06-01)

Preventive bacterial translocation and control of Ventilator-Associated Pneumonia: A qualitative study
by: Yulis Setiya Dewi, et al.
Published: (2022-12-01)

dep1 improves rice grain yield and nitrogen use efficiency simultaneously by enhancing nitrogen and dry matter translocation
by: Li-ying HUANG, et al.
Published: (2022-01-01)

Global Analysis of Cytosine Methylation and Proteome Under Cold Treatment in Brassica napus
by: Fang WEI, et al.
Published: (2014-10-01)

Multi-omics integration reveals chromatin-associated lncRNA prognostic model in lung adenocarcinoma: Bridging GWAS, transcriptome and clinical outcomes
by: Xiao Zhu, et al.
Published: (2025-08-01)

Zinc Translocation from Coastal Soil to Wheat as Mediated by Zinc Supply Levels and Soil Properties
by: Deyong Zhao, et al.
Published: (2025-06-01)

Phytochemical investigation of polyphenolic compounds for Cirsium vulgare (Savi) Ten. of Ukraine flora
by: Y. V. Popova, et al.
Published: (2016-04-01)

Comparative analysis of the ten Tusscher and Tomek human ventricular cell models at cellular, tissue, and organ levels: Implications for post‐infarct ventricular tachycardia simulation
by: Ruiqing Dong, et al.
Published: (2025-07-01)

Pratique des translocations végétales conservatoires en France : dimensions réglementaires, organisationnelles et économiques
by: Mohamed Diallo, et al.
Published: (2023-07-01)

“Ritornare” nella post-migrazione: narrazioni sull’abitare translocale a Serino (AV) - Post-Migration “Return”: Translocal Living Narratives from Serino (AV), Italy
by: Daria De Grazia
Published: (2025-07-01)

Effects of Ammonium on Assimilate Translocation and Storage Root Growth in <i>Sushu16</i> in Root-Swelling Stage
by: Wenjing Yao, et al.
Published: (2025-05-01)

Study on the length of speed change lanes at the entrance and exit of two-way ten-lane expressways
by: Ling Chen, et al.
Published: (2025-07-01)

PERBANDINGAN EFEKTIVITAS SATU PAKET PROGRAM TERAPI SWD DAN TENS TERHADAP PENGURANGAN NYERI PADA PASIEN LOW BACK PAIN MEKANIK
by: Adventina Silalahi, et al.
Published: (2016-11-01)

Genetic effects of Agropyron cristatum 2P chromosome translocation fragments in a wheat background
by: Shi-rui XU, et al.
Published: (2023-01-01)

Ion transport in plants : proceedings of an international meeting, Liverpool, July 1972 /
Published: (1973)

Transport and transfer processes in plants
Published: (1976)

The effect of bacterial overgrowth syndrome and bacterial translocation on the course of liver cirrhosis
by: M. S. Zharkova, et al.
Published: (2012-09-01)

Approximate String Matching with Non-Overlapping Adjacent Unbalanced Translocations
by: Domenico Cantone, et al.
Published: (2025-06-01)

DNA-demethylation by DAC induces MAGE expression and MAGE-specific T cell reactivity against tumors but also healthy cell subsets
by: Marije A.J. de Rooij, et al.
Published: (2025-09-01)

The role of DNA methylation and demethylation in bladder cancer: a focus on therapeutic strategies
by: Wiktoria Strasenburg, et al.
Published: (2025-06-01)