Drug-induced arterial hypertension in a patient with ischemic stroke

Progressive ischemic stroke is the most frequent form of stroke with neurologic deterioration. The pathogenesis of progressive ischemic stroke is based on the expansion of the brain infarction zone and reduction of the "penumbra" zone in the area of focal ischemia. The leading role in main...

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Main Authors: G. R. Ramazanov, E. V. Shevchenko, R. Sh. Muslimov, I. S. Aliev
Format: Article
Language:Russian
Published: Private institution educational organization of higher education "Medical University "ReaViz" 2023-09-01
Series:Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
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Online Access:https://vestnik.reaviz.ru/jour/article/view/808
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author G. R. Ramazanov
E. V. Shevchenko
R. Sh. Muslimov
I. S. Aliev
author_facet G. R. Ramazanov
E. V. Shevchenko
R. Sh. Muslimov
I. S. Aliev
author_sort G. R. Ramazanov
collection DOAJ
description Progressive ischemic stroke is the most frequent form of stroke with neurologic deterioration. The pathogenesis of progressive ischemic stroke is based on the expansion of the brain infarction zone and reduction of the "penumbra" zone in the area of focal ischemia. The leading role in maintaining the balance between irreversible and reversible ischemia belongs to cerebral collateral blood flow. Being a multifactorial phenomenon, collateral blood flow is caused by both morphological and functional characteristics of the collateral arterial channel and systemic factors, among which hemodynamics is of great importance. The tactic of purposeful increase in blood pressure to improve cerebral perfusion is called drug-induced arterial hypertension. A number of experimental studies have demonstrated the safety and efficacy of this method, but the small number and heterogeneity of data in the studies do not allow us to conduct a meta-analysis and form an optimal protocol for drug-induced arterial hypertension. In this article we want to describe the clinical observation of a patient with ischemic stroke on the background of critical stenosis of stroke-related internal carotid artery and atrial fibrillation, in the treatment of which we applied drug-induced arterial hypertension.
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publishDate 2023-09-01
publisher Private institution educational organization of higher education "Medical University "ReaViz"
record_format Article
series Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
spelling doaj-art-b92f48ba7a5e44b28fdc6dea9cc6d3c22025-08-03T13:33:57ZrusPrivate institution educational organization of higher education "Medical University "ReaViz"Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье2226-762X2782-15792023-09-0113412713310.20340/vmi-rvz.2023.4.CASE.4488Drug-induced arterial hypertension in a patient with ischemic strokeG. R. Ramazanov0E. V. Shevchenko1R. Sh. Muslimov2I. S. Aliev3Sklifosovsky Emergency Medicine InstituteSklifosovsky Emergency Medicine InstituteSklifosovsky Emergency Medicine InstituteSklifosovsky Emergency Medicine InstituteProgressive ischemic stroke is the most frequent form of stroke with neurologic deterioration. The pathogenesis of progressive ischemic stroke is based on the expansion of the brain infarction zone and reduction of the "penumbra" zone in the area of focal ischemia. The leading role in maintaining the balance between irreversible and reversible ischemia belongs to cerebral collateral blood flow. Being a multifactorial phenomenon, collateral blood flow is caused by both morphological and functional characteristics of the collateral arterial channel and systemic factors, among which hemodynamics is of great importance. The tactic of purposeful increase in blood pressure to improve cerebral perfusion is called drug-induced arterial hypertension. A number of experimental studies have demonstrated the safety and efficacy of this method, but the small number and heterogeneity of data in the studies do not allow us to conduct a meta-analysis and form an optimal protocol for drug-induced arterial hypertension. In this article we want to describe the clinical observation of a patient with ischemic stroke on the background of critical stenosis of stroke-related internal carotid artery and atrial fibrillation, in the treatment of which we applied drug-induced arterial hypertension.https://vestnik.reaviz.ru/jour/article/view/808cerebral collateral blood flowischemic strokeperfusionpenumbrabaseline therapy
spellingShingle G. R. Ramazanov
E. V. Shevchenko
R. Sh. Muslimov
I. S. Aliev
Drug-induced arterial hypertension in a patient with ischemic stroke
Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
cerebral collateral blood flow
ischemic stroke
perfusion
penumbra
baseline therapy
title Drug-induced arterial hypertension in a patient with ischemic stroke
title_full Drug-induced arterial hypertension in a patient with ischemic stroke
title_fullStr Drug-induced arterial hypertension in a patient with ischemic stroke
title_full_unstemmed Drug-induced arterial hypertension in a patient with ischemic stroke
title_short Drug-induced arterial hypertension in a patient with ischemic stroke
title_sort drug induced arterial hypertension in a patient with ischemic stroke
topic cerebral collateral blood flow
ischemic stroke
perfusion
penumbra
baseline therapy
url https://vestnik.reaviz.ru/jour/article/view/808
work_keys_str_mv AT grramazanov druginducedarterialhypertensioninapatientwithischemicstroke
AT evshevchenko druginducedarterialhypertensioninapatientwithischemicstroke
AT rshmuslimov druginducedarterialhypertensioninapatientwithischemicstroke
AT isaliev druginducedarterialhypertensioninapatientwithischemicstroke