Active Detoxification in the Treatment of Abdominal Sepsis
Objective: to evaluate the efficiency of extracorporeal detoxification techniques in patients with abdominal sepsis. Subjects and methods. Three hundred and seventy-nine patients with acute generalized peritonitis were examined. Extracorporeal detoxifying techniques were used during conventional the...
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2009-02-01
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| Series: | Общая реаниматология |
| Online Access: | https://www.reanimatology.com/rmt/article/view/622 |
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| author | O. M. Shevtsova N. V. Shapovalova T. N. Sviridova Yu. V. Struk |
| author_facet | O. M. Shevtsova N. V. Shapovalova T. N. Sviridova Yu. V. Struk |
| author_sort | O. M. Shevtsova |
| collection | DOAJ |
| description | Objective: to evaluate the efficiency of extracorporeal detoxification techniques in patients with abdominal sepsis. Subjects and methods. Three hundred and seventy-nine patients with acute generalized peritonitis were examined. Extracorporeal detoxifying techniques were used during conventional therapy in Group 1 (n=319); the other patients received only traditional therapy (a control group). The time course of changes in the parameters of toxemia, a hemostasiogram, and an immunogram were examined. Results. The study indicated significantly reduced endotoxemia and better blood aggregation resulting from the use of plasmapheresis, cryoplasmasorption, and plasmasorption, as well as stimulated immunity when the above techniques were combined with autoblood photomodification and extracorporeal immunopharmacotherapy in patients with abdominal sepsis. In severe abdominal sepsis and infectious-toxic shock, there was regression of multiple organ dysfunction and lower mortality when venovenous hemofiltration was applied. Conclusion. A differential approach to using active detoxifying techniques is needed, by taking into account the severity of the disease. Key words: abdominal sepsis, detoxifying techniques. |
| format | Article |
| id | doaj-art-b8a1791da43f4802af33d7c87b3f64a0 |
| institution | Matheson Library |
| issn | 1813-9779 2411-7110 |
| language | English |
| publishDate | 2009-02-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj-art-b8a1791da43f4802af33d7c87b3f64a02025-08-04T10:40:39ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102009-02-015110.15360/1813-9779-2009-1-37622Active Detoxification in the Treatment of Abdominal SepsisO. M. ShevtsovaN. V. ShapovalovaT. N. SviridovaYu. V. StrukObjective: to evaluate the efficiency of extracorporeal detoxification techniques in patients with abdominal sepsis. Subjects and methods. Three hundred and seventy-nine patients with acute generalized peritonitis were examined. Extracorporeal detoxifying techniques were used during conventional therapy in Group 1 (n=319); the other patients received only traditional therapy (a control group). The time course of changes in the parameters of toxemia, a hemostasiogram, and an immunogram were examined. Results. The study indicated significantly reduced endotoxemia and better blood aggregation resulting from the use of plasmapheresis, cryoplasmasorption, and plasmasorption, as well as stimulated immunity when the above techniques were combined with autoblood photomodification and extracorporeal immunopharmacotherapy in patients with abdominal sepsis. In severe abdominal sepsis and infectious-toxic shock, there was regression of multiple organ dysfunction and lower mortality when venovenous hemofiltration was applied. Conclusion. A differential approach to using active detoxifying techniques is needed, by taking into account the severity of the disease. Key words: abdominal sepsis, detoxifying techniques.https://www.reanimatology.com/rmt/article/view/622 |
| spellingShingle | O. M. Shevtsova N. V. Shapovalova T. N. Sviridova Yu. V. Struk Active Detoxification in the Treatment of Abdominal Sepsis Общая реаниматология |
| title | Active Detoxification in the Treatment of Abdominal Sepsis |
| title_full | Active Detoxification in the Treatment of Abdominal Sepsis |
| title_fullStr | Active Detoxification in the Treatment of Abdominal Sepsis |
| title_full_unstemmed | Active Detoxification in the Treatment of Abdominal Sepsis |
| title_short | Active Detoxification in the Treatment of Abdominal Sepsis |
| title_sort | active detoxification in the treatment of abdominal sepsis |
| url | https://www.reanimatology.com/rmt/article/view/622 |
| work_keys_str_mv | AT omshevtsova activedetoxificationinthetreatmentofabdominalsepsis AT nvshapovalova activedetoxificationinthetreatmentofabdominalsepsis AT tnsviridova activedetoxificationinthetreatmentofabdominalsepsis AT yuvstruk activedetoxificationinthetreatmentofabdominalsepsis |