Complex Assessment of the Functional State of the Urinary System in Preclinical Studies. Part 1. Instrumental and Laboratory Assessment Methods (Review)

Complex Assessment of the Functional State of the Urinary System in Preclinical Studies. Part 1. Instrumental and Laboratory Assessment Methods (Review)

INTRODUCTION. Functional examination of the urinary system, and particularly the kidneys, is an important challenge in preclinical studies. Currently, there is no generally recognised and detailed approach to drug-induced nephrotoxicity detection in vivo, nor are there clear criteria for its assessm...

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Bibliographic Details
Main Authors: M. V. Miroshnikov, K. T. Sultanova, M. N. Makarova, N. M. Faustova, S. O. Khan, E. A. Loseva
Format: Article
Language:Russian
Published: Federal State Budgetary Institution ‘Scientific Centre for Expert Evaluation of Medicinal Products’ of the Ministry of Health of the Russian Federation (FSBI ‘SCEEMP’) 2024-07-01
Series:Регуляторные исследования и экспертиза лекарственных средств
Subjects:
preclinical studies
kidneys
nephrotoxicity
urinary system
urine
urinalysis
laboratory animals
ultrasonography
usg
necropsy
Online Access:https://www.vedomostincesmp.ru/jour/article/view/629
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