Neonatal testosterone exposure alleviates female-specific severity of formalin-induced inflammatory pain in mice

Neonatal testosterone exposure alleviates female-specific severity of formalin-induced inflammatory pain in mice

Gonadal hormones may influence higher pain sensitivity in females than males by transiently activating the central pain pathway and organizing sexually dimorphic neuronal circuits during development. The latter effects of gonadal hormones, called organizational effects, are critical for establishing...

Full description

Saved in:
Bibliographic Details
Main Authors: Moeko Kanaya, Yoshifumi Ueta, Makiko Mochizuki-Kashio, Ayako Nakamura-Ishizu, Mariko Miyata
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Neural Circuits
Subjects:
organizational effects
Gonadal hormones
formalin test
masculinization
BNST
PAG
Online Access:https://www.frontiersin.org/articles/10.3389/fncir.2025.1593443/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items