Case Report: Neonatal right atrial mass of uncertain etiology
BackgroundNeonatal intracardiac masses are rare and pose significant diagnostic and therapeutic challenges, particularly in differentiating thrombi from tumors.Case summaryWe present the case of a preterm neonate with a right atrial mass of uncertain etiology. Multimodal imaging, including echocardi...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Pediatrics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2025.1621500/full |
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| Summary: | BackgroundNeonatal intracardiac masses are rare and pose significant diagnostic and therapeutic challenges, particularly in differentiating thrombi from tumors.Case summaryWe present the case of a preterm neonate with a right atrial mass of uncertain etiology. Multimodal imaging, including echocardiography and cardiac MRI, suggested the presence of a thrombus—consistent with thrombi being the most common type of intracavitary cardiac mass. As a result, primary anticoagulation therapy was initiated. However, after 16 days without significant change in the mass and given the high risk of embolization and the possibility of a benign tumor, surgical excision was performed. Histopathological analysis of the excised tissue could not definitively distinguish between an organized thrombus and a regressed benign neoplasm, although no malignant cells were identified.ConclusionsThis case highlights the diagnostic uncertainty surrounding neonatal intracardiac masses and the limitations of imaging and pathology in achieving definitive diagnosis. A multidisciplinary approach and long-term follow-up are essential, particularly when the true nature of the mass remains unclear. |
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| ISSN: | 2296-2360 |