THE PROBLEMS ASSOCIATED WITH SWITCHING BRAND-NAME ANTIEPILEPTIC DRUGS TO GENERICS: A FOCUS ON TOPAMAX: A REVIEW OF LITERATURE AND A CASE REPORT
Despite the rather high efficiency of treatment for epilepsy (overall, 65–70 % of patients can achieve remission or show a considerable decrease in the frequency of seizures), there remains a challenge due to the need to use antiepileptic drugs long and regularly: therapy adherence, compliance, trea...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2016-08-01
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| Series: | Русский журнал детской неврологии |
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| Online Access: | https://rjdn.abvpress.ru/jour/article/view/152 |
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| author | K. Yu. Mukhin O. A. Pylaeva M. Yu. Bobylova |
| author_facet | K. Yu. Mukhin O. A. Pylaeva M. Yu. Bobylova |
| author_sort | K. Yu. Mukhin |
| collection | DOAJ |
| description | Despite the rather high efficiency of treatment for epilepsy (overall, 65–70 % of patients can achieve remission or show a considerable decrease in the frequency of seizures), there remains a challenge due to the need to use antiepileptic drugs long and regularly: therapy adherence, compliance, treatment tolerability, and impact of therapy on quality of patent’s life. One of the aspects of this problem is a very common tendency to switch brand-name antiepileptic drugs to their generics that are 1ess expensive, but also less predictably effective and tolerable. The authors review the literature on the interchangeability of brand-name and generic drugs and describe their case. |
| format | Article |
| id | doaj-art-b79cf3d0e1e04ccfb25a2a99d9e8c8ac |
| institution | Matheson Library |
| issn | 2073-8803 2412-9178 |
| language | Russian |
| publishDate | 2016-08-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Русский журнал детской неврологии |
| spelling | doaj-art-b79cf3d0e1e04ccfb25a2a99d9e8c8ac2025-08-04T14:12:11ZrusABV-pressРусский журнал детской неврологии2073-88032412-91782016-08-01112425110.17650/2073-8803-2016-11-2-42-51120THE PROBLEMS ASSOCIATED WITH SWITCHING BRAND-NAME ANTIEPILEPTIC DRUGS TO GENERICS: A FOCUS ON TOPAMAX: A REVIEW OF LITERATURE AND A CASE REPORTK. Yu. Mukhin0O. A. Pylaeva1M. Yu. Bobylova2Svt. Luka's Institute of Child Neurology and Epilepsy, MoscowSvt. Luka's Institute of Child Neurology and Epilepsy, MoscowSvt. Luka's Institute of Child Neurology and Epilepsy, MoscowDespite the rather high efficiency of treatment for epilepsy (overall, 65–70 % of patients can achieve remission or show a considerable decrease in the frequency of seizures), there remains a challenge due to the need to use antiepileptic drugs long and regularly: therapy adherence, compliance, treatment tolerability, and impact of therapy on quality of patent’s life. One of the aspects of this problem is a very common tendency to switch brand-name antiepileptic drugs to their generics that are 1ess expensive, but also less predictably effective and tolerable. The authors review the literature on the interchangeability of brand-name and generic drugs and describe their case.https://rjdn.abvpress.ru/jour/article/view/152epilepsyantiepileptic drugbrand-name druggeneric drugbioequivalenceefficiency of treatmenttolerability of treatment |
| spellingShingle | K. Yu. Mukhin O. A. Pylaeva M. Yu. Bobylova THE PROBLEMS ASSOCIATED WITH SWITCHING BRAND-NAME ANTIEPILEPTIC DRUGS TO GENERICS: A FOCUS ON TOPAMAX: A REVIEW OF LITERATURE AND A CASE REPORT Русский журнал детской неврологии epilepsy antiepileptic drug brand-name drug generic drug bioequivalence efficiency of treatment tolerability of treatment |
| title | THE PROBLEMS ASSOCIATED WITH SWITCHING BRAND-NAME ANTIEPILEPTIC DRUGS TO GENERICS: A FOCUS ON TOPAMAX: A REVIEW OF LITERATURE AND A CASE REPORT |
| title_full | THE PROBLEMS ASSOCIATED WITH SWITCHING BRAND-NAME ANTIEPILEPTIC DRUGS TO GENERICS: A FOCUS ON TOPAMAX: A REVIEW OF LITERATURE AND A CASE REPORT |
| title_fullStr | THE PROBLEMS ASSOCIATED WITH SWITCHING BRAND-NAME ANTIEPILEPTIC DRUGS TO GENERICS: A FOCUS ON TOPAMAX: A REVIEW OF LITERATURE AND A CASE REPORT |
| title_full_unstemmed | THE PROBLEMS ASSOCIATED WITH SWITCHING BRAND-NAME ANTIEPILEPTIC DRUGS TO GENERICS: A FOCUS ON TOPAMAX: A REVIEW OF LITERATURE AND A CASE REPORT |
| title_short | THE PROBLEMS ASSOCIATED WITH SWITCHING BRAND-NAME ANTIEPILEPTIC DRUGS TO GENERICS: A FOCUS ON TOPAMAX: A REVIEW OF LITERATURE AND A CASE REPORT |
| title_sort | problems associated with switching brand name antiepileptic drugs to generics a focus on topamax a review of literature and a case report |
| topic | epilepsy antiepileptic drug brand-name drug generic drug bioequivalence efficiency of treatment tolerability of treatment |
| url | https://rjdn.abvpress.ru/jour/article/view/152 |
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